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Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.

Researchers found genes linked to feather growth speed in Shouguang chickens, highlighting two genes that might explain differences in feathering.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Ets2 gene is crucial for placental development in mice.

Key genes linked to important traits in Chinese sheep and goats have been identified, but challenges remain in breeding improvements.

Platelet-derived exosomes offer better regenerative therapy but face challenges in isolation and regulation.

Constant-release melatonin reduces SOX21 gene expression in goats during the hair follicle resting phase.

The study created a mouse model that survives longer and shows fewer symptoms of pemphigus vulgaris.

Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.

Exosomes from different stem cell sources affect immune cells and brain cell growth differently.

Exosomes from modified stem cells may help treat liver injury.

Exosomes from stem cells help repair irradiated salivary glands by boosting cell growth.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

The guinea pig α-lactalbumin gene was successfully expressed in the mammary glands of transgenic mice.

The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.

LGR6+ stem cells may improve bone healing.

Two genes, ERBB4 and ROR1, may cause the unique pigmentation in Lanping black-boned sheep.

The research identified new skin traits in mice, some linked to human skin conditions.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.

Bone marrow stem cells from Guizhou miniature pigs can grow well and become different cell types, useful for tissue engineering.

Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Epidermal stem cells improve skin graft survival by promoting early blood vessel formation.