research Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model
FLASH radiation reduces tissue damage more than conventional radiation.
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690-720 / 1000+ resultsresearch Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinoma
Doxil's toxicity varies with dose and schedule, and pharmacokinetic guidance can optimize dosing.
research Assessment of the toxicity of the crude extract of Hibiscus rosa-sinensis Linn. leaves and the effect of gamma radiation on this extract
Gamma radiation enhances the antioxidant properties of Hibiscus rosa-sinensis extract without causing toxicity.
research Heat treatment increases the incidence of alopecia areata in the C3H/HeJ mouse model
Heat treatment increases hair loss in certain mice.
research Selenium Poisoning From a Nutritional Supplement
Taking too many selenium supplements can cause serious health problems like hair loss and fatigue.
research SIDE EFFECTS OF CYCLOSPORINE COMPARED TO TACROLIMUS AMONG YEMENI KIDNEY TRANSPLANT PATIENTS WHO SHARE THE SAME ADJUVANT AGENTS: MYCOPHENOLATE MOFETIL AND PREDNISONE
Tacrolimus is a better option than cyclosporine due to fewer side effects.
research Accidental Poisoning with Autumn Crocus
Accidentally eating autumn crocus can cause long-term health issues.
research From Russia with Love
Dr. Marina Kovalevsky and her daughter were hospitalized for suspected politically motivated thallium poisoning in Moscow.
research Continuous MEK inhibition by AZD6244 (ARRY-142886) results in exhaustion of the cutaneous keratinocytic stem cell pool and resembles senescence driven skin aging
AZD6244 treatment causes skin aging effects by depleting skin stem cells.
research Dermatological adverse events with taxane chemotherapy
Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
research Protoporphyrin IX: the Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research Nanoparticle systems reduce systemic toxicity in cancer treatment
Nanoparticle systems make cancer treatment less toxic.
research LBODP010 A Case of Glucocorticoid Resistance Syndrome
The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.
research The Monophenolic Antioxidant TS-13 Accelerates Hair Restoration in Mice with Chemotherapy-Induced Alopecia
TS-13 speeds up hair regrowth after chemotherapy without affecting treatment effectiveness.
research Methotrexate injection site reactions: Case report and literature review
Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.
research 452: HAIR-RAISING TOXICITY: STATUS EPILEPTICUS FOLLOWING HAIR RESTORATION DUE TO LAST AND TXA TOXICITY
Hair restoration can cause severe seizures due to combined drug toxicity.
research Neurosteroid Synthesis-Mediated Regulation of GABAAReceptors: Relevance to the Ovarian Cycle and Stress
Ovarian and stress hormones can change GABA A receptors through neurosteroids.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Lithium toxicity profi le: a systematic review and meta-analysis
Lithium can cause some health issues, but severe risks are low.
research Topical absorption and systemic toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Effects of mitotane treatment on human steroid metabolism: implications for patient management
Mitotane changes steroid breakdown, affecting cortisol availability.
research Targeting sonic hedgehog (shh) signaling pathways by the concentration–dependent topical resveratrol for protection from cyclophosphamide-induced alopecia in a mouse model
research Toxicosis in pigs fed selenium-accumulating Astragalus plant species or sodium selenate
High selenium diets in pigs cause health issues like weight loss, hair loss, and nerve damage.
research Introduction to this second series of Biometals webinars, The biology of mammalian multi-copper ferroxidases, Arsenic antibiotics: old and new
Some bacteria use arsenic compounds as antibiotics, and others have evolved resistance; a particular arsenic-based compound shows potential as a new antimalarial treatment.
research Cutaneous complications of chemotherapeutic agents
Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
research Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants
Natural antioxidants may help prevent hair loss by reducing oxidative stress.
research The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome
Diet changes can protect against harmful environmental effects on fetal development.
research Senile hair graying: H 2 O 2 ‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
Gray hair is caused by hydrogen peroxide buildup, which damages hair color repair.
research Evaluation of Potential Toxicity of Calotropis gigantea Leaf Extract on Danio rerio: Bioactive Compounds, Oxidative Stress and Histological Toxicity Analysis
Calotropis gigantea leaf extract causes significant tissue damage and stress in fish.