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GlossaryTelomerase Reverse Transcriptase

enzyme that maintains telomere length, crucial for cell division

Telomerase Reverse Transcriptase (TERT) is an enzyme that helps maintain the length of telomeres, which are protective caps at the ends of chromosomes. By adding repetitive nucleotide sequences to the telomeres, TERT plays a crucial role in cellular aging and replication. This enzyme is particularly active in stem cells, germ cells, and cancer cells, allowing them to divide indefinitely.

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Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease

research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease

11 citations , January 2000 in “Journal of Cutaneous Pathology”

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

research Molecular Regulation of Melanocyte Senescence

85 citations , July 2002 in “Pigment Cell Research”

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

research Dermal papilla cells induce keratinocyte tubulogenesis in culture

28 citations , March 2010 in “Histochemistry and cell biology”

Skin cells can help create early hair-like structures in lab cultures.

research TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo

1 citations , March 2022 in “Journal of Dermatological Science”

Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.

Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions

research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions

September 2023 in “Journal of Nutrition and Metabolism”

One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.

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community Hyperbaric Oxygen Therapy (HBOT)

in Research/Science 8 upvotes 4 years ago

Hyperbaric Oxygen Therapy (HBOT) is discussed as a potential treatment for androgenic alopecia due to its ability to reverse hypoxia and promote angiogenesis. The conversation explores its potential benefits for hair loss, though no studies have been conducted on this application yet.

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