research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
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5 / 294 results research Tmprss2: A Key Host Factor In SARS-CoV-2 Infection And Potential Therapeutic Target
TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.
research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research The Secret Identities of TMPRSS2: Fertility Factor, Virus Trafficker, Inflammation Moderator, Prostate Protector and Tumor Suppressor
TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
research Analyzing the Role of ACE2, AR, MX1, and TMPRSS2 Genetic Markers for COVID-19 Severity
MX1 and AR genes are linked to milder COVID-19, while TMPRSS2 increases severe risk, especially in women.
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1 / 1 resultscommunity Adrogens and Covid-19
The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.