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GlossaryAlopecia Universalis

complete loss of all body and scalp hair

Alopecia Universalis (AU) is a severe form of alopecia areata characterized by the complete loss of hair on the scalp and body, including eyebrows and eyelashes. It is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to total hair loss.

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Research

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research PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology

105 citations , December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

PUVA treatment is generally ineffective for alopecia areata.

research Anti-SRP Antibody-positive Myopathy with Universal Alopecia and Multiple Vitiligo

1 citations , January 2015 in “Acta Dermato Venereologica”

Autoimmune myopathy may be linked to hair loss and skin depigmentation.

The Development of Universal Alopecia During Therapy With TNF-α Inhibitors in Patients With Ankylosing Spondylitis: Description of Three Cases

research The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases

October 2021 in “Rheumatology Science and Practice”

TNF-α inhibitors may cause complete hair loss in some patients with ankylosing spondylitis.

The Use of Tofacitinib in the Treatment of Immune-Mediated Universal Alopecia in a Patient with Systemic Lupus Erythematosus: A Case Report

research THE USE OF TOFACITINIB IN THE TREATMENT OF IMMUNE-MEDIATED UNIVERSAL ALOPECIA IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT

January 2021 in “Anais do Congresso Brasileiro de Reumatologia 2020”

Tofacitinib improved arthritis and partially improved hair loss in a lupus patient without side effects.

research Efficacy of Tofacitinib in the Treatment of Universal Alopecia Areata and Primary Sjögren Syndrome

April 2023 in “Dermato”

Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.

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Community Join

5 / 221 results

community Alopecia Areata Question

in Treatment 2 upvotes 5 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community No hair, don't care! [24/F] :)

60 upvotes 10 years ago

A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 677 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Olumiant alternative for Alopecia Areata?

in Treatment 1 upvotes 3 years ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community The mechanism of androgenic alopecia

in Research/Science 34 upvotes 9 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

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