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GlossaryVemurafenib

medication treats melanoma with BRAF gene mutation

Vemurafenib is a medication used to treat certain types of cancer, specifically melanoma with a mutation in the BRAF gene. It works by inhibiting the activity of the mutated BRAF protein, which helps slow down or stop the growth of cancer cells.

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research RASopathic Skin Eruptions during Vemurafenib Therapy

82 citations , March 2013 in “PLoS ONE”

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

research RASopathic alopecia: Hair changes associated with vemurafenib therapy

21 citations , March 2015 in “Journal of The American Academy of Dermatology”

Vemurafenib therapy can cause hair loss, but clobetasol propionate foam can help regrow hair.

research Vemurafenib-induced pityriasis amiantacea: a case report

9 citations , October 2015 in “Cutaneous and ocular toxicology”

Vemurafenib can cause scalp issues but can be managed without changing the dose.

research Correction: RASopathic Skin Eruptions during Vemurafenib Therapy

4 citations , October 2013 in “PLoS ONE”

Vemurafenib causes significant skin side effects, requiring regular dermatologist care and sun protection.

research Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma

32 citations , May 2016 in “European journal of dermatology/EJD. European journal of dermatology”

Targeted therapies for advanced skin cancer often cause hair and nail problems, which need managing to avoid changing the treatment dose.

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