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GlossarySorafenib

medication that inhibits proteins to slow cancer growth

Sorafenib is a medication primarily used to treat certain types of cancer, such as liver, kidney, and thyroid cancers. It works by inhibiting multiple proteins involved in tumor cell growth and angiogenesis (the formation of new blood vessels that supply the tumor), thereby slowing the progression of the disease.

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research Hand-Foot and Stump Syndrome to Sorafenib

45 citations , January 2007 in “Journal of Clinical Oncology”

Sorafenib may cause hand-foot and stump syndrome, requiring early detection and management.

research Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea

39 citations , June 2019 in “Frontiers in Endocrinology”

Lenvatinib and sorafenib are generally safe but need dose adjustments due to side effects.

research Sorafenib-induced eruption resembling pityriasis rubra pilaris

21 citations , July 2011 in “Journal of the American Academy of Dermatology”

A man developed a rash similar to pityriasis rubra pilaris after starting sorafenib for cancer, possibly due to the drug's effect on skin cells.

Sorafenib Combined with Hepatectomy in Patients with Intermediate-Stage and Advanced Hepatocellular Carcinoma

research Sorafenib combined with hepatectomy in patients with intermediate-stage and advanced hepatocellular carcinoma

16 citations , January 2017 in “Archives of Medical Science”

Sorafenib after liver surgery may increase survival for some liver cancer patients.

Sorafenib-Associated Facial Acneiform Eruption

research Sorafenib-Associated Facial Acneiform Eruption

15 citations , December 2014 in “Dermatology and therapy”

Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.

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