Original Study: Comparison of Androgen Receptor Expression in Lesional and Non-Lesional Areas of Androgenetic Alopecia

    January 1994 in “ 대한피부과학회지
    이원수, 정준, 이승헌, 안성구
    TLDR Androgen receptor expression is similar in affected and unaffected scalp areas in androgenetic alopecia.
    The study aimed to compare androgen receptor expression in lesional and non-lesional scalp areas of androgenetic alopecia patients using immunohistochemical staining. Biopsy specimens from 3 patients with androgenetic alopecia and 4 normal controls were analyzed. Results showed that androgen receptors were strongly expressed in eccrine and sebaceous glands, and weakly in epidermal cells, hair infundibulum, hair bulb epithelium, and dermal hair papilla. The study concluded that there was no significant difference in androgen receptor expression between lesional and non-lesional scalp areas in patients with androgenetic alopecia.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 1 year ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 6 months ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

    Similar Research

    5 / 1000+ results