Topical Finasteride: A Potential Therapeutic Option for Hidradenitis Suppurativa

    September 2022 in “ Dermatologic Therapy
    Marco Manfredini, Antonio Alma, Linda Pongetti, Alberto Sticchi, Baschieri E, Francesca Farnetani, Giovanni Pellacani
    This study explored the use of topical finasteride as a treatment for hidradenitis suppurativa (HS) in a small cohort of 4 male patients. Over a period of 3 months, patients applied topical finasteride to affected areas, resulting in clinical improvement and enhanced quality of life. The average reduction in the International Hidradenitis Suppurativa Severity Score System (IHS4) was 3.75, and the Dermatology Life Quality Index (DLQI) improved by 8.5 points. Although the Hurley stage remained unchanged, the findings suggested that topical finasteride could be a promising treatment option for HS by inhibiting local hyperandrogenism. However, the study emphasized the need for larger studies to confirm these results.
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