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GlossaryDermal Papilla Cells

specialized cells at hair follicle base crucial for hair growth

Dermal Papilla Cells (DPCs) are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by interacting with surrounding cells to regulate the hair growth cycle. These cells are essential for the formation of new hair follicles and are a key focus in research on hair loss treatments and regenerative medicine.

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Research

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research Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties

5 citations , February 2023 in “Frontiers in Veterinary Science”

Ovine dermal papilla cells are promising for hair growth research due to their stable properties and hair-inducing abilities.

research Effects of Natural Herbal Marker Compounds on Human Dermal Papilla Cell Growth Regulation

December 2023

Four natural compounds were found to promote hair growth effectively.

research Teicoplanin alleviates androgenetic alopecia through inhibition of androgen receptor expression and enhancing dermal papilla cell proliferation

February 2026 in “European Journal of Pharmacology”

Teicoplanin may help treat hair loss by reducing androgen receptors and boosting hair cell growth.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations , January 2014 in “BioMed research international”

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

research 1361 A novel cell surface marker for hair follicle dermal cells throughout hair morphogenesis and cycling

April 2018 in “Journal of Investigative Dermatology”

Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.

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Community Join

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community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

in Research/Science 8 upvotes 4 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community Epibiotech will now offer off-the-shelf allogeneic hair multiplication treatment in South Korea

in Research/Science 80 upvotes 4 years ago

Epibiotech will offer off-the-shelf allogeneic hair multiplication treatment in South Korea, using dermal papilla cells from donors to grow hair in balding areas. This method is cheaper and less invasive than traditional hair transplants.

community HairClone developing cell replacement treatments for Hair Loss

4 upvotes 7 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 30 upvotes 4 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community A Theory on Why Microneedling Works

170 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Stem Cell Factor

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

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