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GlossaryFractional Lasers

target small skin areas to boost collagen and rejuvenation

Fractional lasers, also known as fractional laser therapy or fractional laser resurfacing, are a type of laser treatment that targets small, precise areas of the skin to promote collagen production and skin rejuvenation. By creating microscopic columns of treated skin surrounded by untreated tissue, these lasers help in faster healing and are commonly used for reducing wrinkles, scars, and pigmentation issues.

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Research

5 / 1000+ results

research Synergistic Effects of Fractional CO ₂ Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling

January 2025 in “Dermatologic Therapy”

Combining fractional CO₂ laser with type III collagen improves acne scar treatment.

research The Efficacy and Safety of Ablative Fractional CO ₂ Laser Combined With Topical Minoxidil for Male Androgenetic Alopecia: A Randomized Clinical Trial

January 2026 in “Dermatologic Therapy”

Combining laser treatment with minoxidil is more effective for hair growth in men than using minoxidil alone.

research Efficacy and Safety of Ablative Fractional CO ₂ Laser Therapy for Localized Scleroderma: A Comprehensive Bench‐to‐Bedside Approach

January 2025 in “Dermatologic Therapy”

CO₂ laser therapy improves skin and hair growth in localized scleroderma without severe side effects.

Faculty Opinions Recommendation of Treatment of Alopecia Areata with Nonablative Fractional Laser Combined with Topical Minoxidil

research Faculty Opinions recommendation of Treatment of alopecia areata with nonablative fractional laser combined with topical minoxidil.

March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Combining nonablative fractional laser with minoxidil was effective for alopecia areata with only one patient relapsing after a year.

research Expression of collagen type I, skin fibroblasts and macrophages after 1550 nm erbium glass fractional laser in androgenic alopecia

January 2020

The 1550 nm fractional Er:Glass laser improved hair regrowth in patients with androgenic alopecia, but didn't significantly change collagen type I, skin fibroblasts, or macrophages. More research is needed for optimal results.

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Community Join

5 / 309 results

community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 108 upvotes 5 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community Dr Huberman - Cafeine when rubbed on the scalp can be as effective at times as minoxidil because it triggers 1GF-1

in Update 268 upvotes 3 years ago

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

community What's "wrong" with oral minoxidil, exactly?

in Minoxidil 173 upvotes 1 year ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community [13-Year Hair Loss Journey – Reached Norwood 7, Trying Again in 2025 (Male, 32, Vietnam)]

in Progress Pictures 243 upvotes 9 months ago

A 32-year-old man from Vietnam, at Norwood 7 hair loss, is using Minoxidil, Finasteride, rosemary oil, NMN, and CoQ10 to regrow hair. Despite minor improvements, alternatives like hair systems or accepting baldness are suggested due to advanced hair loss.

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Learn

2 / 801 results

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Experts

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23
Hair Transplant Surgeon
Dr. Chaka Co
Rotterdam, Netherlands

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Dr. Chaka Co