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GlossaryU2HR protein

truncated protein inhibiting hair growth gene, affecting follicles

The U2HR protein is a truncated form of the U2HR (U2 Hairless Repressor) gene product, which plays a role in hair growth regulation. It acts as an inhibitor of the hairless (HR) gene, which is crucial for hair follicle cycling and maintenance. By interfering with the HR gene's function, the U2HR protein can potentially lead to conditions like alopecia, where hair growth is disrupted.

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research Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA

3 citations , February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine”

A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.

research The “Bald Mill Hill” Mutation in the Mouse Is Associated with an Abnormal, Mislocalized HR bmh Protein

1 citations , July 2007 in “Journal of Investigative Dermatology”

The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.

research The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm

January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.

research In Silico Characterization and Analysis of Clinically Significant Variants of Lipase-H (LIPH Gene) Protein Associated with Hypotrichosis

May 2023 in “Pharmaceuticals”

Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.

research Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers

15 citations , May 2017 in “Journal of Cellular Biochemistry”

The hairless protein is important for skin, hair, and may influence cancer development.

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community Does whey protein and creatine aggravate hair loss?

in Research/Science 83 upvotes 2 years ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community What regimen do I need to get this hairline?

in Satire 362 upvotes 3 years ago

Discussing a regimen to improve the user's hairline, with treatments proposed including minoxidil, rectal microneedling, IV drip of minoxidil, laser removal, PRP injection, topical minoxidil, divine protein shakes, stem cell injections, and keto shampoo.

community + 5 years Finasteride and dermarroll journey PICS and ACTUAL DILEMMA

in Progress Pictures 54 upvotes 2 years ago

The user experienced improved hair density and thickness after using finasteride and dermarolling for 2.5 years but noticed hair loss when doing anaerobic exercise. They increased their finasteride dose and continued dermarolling but are considering not starting minoxidil due to its perceived hassle and uncertain long-term benefits.

community 4 months, only Minoxidil 5% ,dermarolling twice a week. hair growth results. any suggestions?

in Minoxidil 461 upvotes 1 year ago

Significant hair growth was achieved using Minoxidil 5% and dermarolling twice a week, with suggestions to add finasteride for maintenance. There is debate on when to apply Minoxidil after dermarolling to avoid irritation.

community 1 year 1 month 1mg finasteride 2.5mg oral minoxidil (eyebrow + scalp gains)

in Progress Pictures 178 upvotes 1 year ago

The conversation is about a user's positive experience with hair regrowth using 1mg finasteride and 2.5mg oral minoxidil, noting improvements in scalp and eyebrow hair. The user mentions minimal side effects, such as a slight increase in heart rate, and prefers oral minoxidil over topical due to ease of use.

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learn sh-Polypeptide-7

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