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research A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n (K17n), Exhibits Preferred Expression in Nail Tissue

31 citations , April 2004 in “Journal of Investigative Dermatology”

A new mouse gene, Keratin 17n, is mainly found in nail tissue and may explain why mice without Keratin 17 don't have nail issues.

research Charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping

10 citations , November 2017 in “Letters in drug design & discovery”

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

research The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis

11 citations , April 2012 in “Journal of Investigative Dermatology”

A specific mutation in PA-PLA1α causes abnormal hair growth.

research O 17-6 Carcinome améloblastique mandibulaire

September 2005 in “Revue de Stomatologie et de Chirurgie Maxillo-faciale”

Genotypes of Single-Nucleotide Polymorphisms on DENND1A in Association with Polycystic Ovary Syndrome Among Saudi Arabian Females

research Genotypes of Single-nucleotide polymorphisms on DENND1A in an association with polycystic ovary syndrome among Saudi Arabian females

July 2025

SNP rs2479106 in the DENND1A gene may increase PCOS risk in Saudi Arabian females.

research Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family

11 citations , May 2013 in “Journal of Investigative Dermatology”

KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

37 citations , January 1993 in “Journal of Investigative Dermatology”

research A Clinical Study of Androgenetic Alopecia(IV)

January 2002 in “Journal of Clinical Dermatology”

research A novel 22-bp InDel within FGF7 gene is significantly associated with growth traits in goat

6 citations , October 2023 in “Animal Biotechnology”

A specific gene variation in goats is linked to better growth traits.

research Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia

114 citations , May 2001 in “Development”

Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.

research Complete sequence of a hair-like intermediate filament type II keratin gene

15 citations , January 1993 in “DNA sequence”

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

research Novel Vitamin D Receptor Mutations in Hereditary Vitamin D Resistant Rickets in Chinese

10 citations , September 2015 in “PLoS ONE”

New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.

research The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties

46 citations , December 1998 in “Journal of Biological Chemistry”

Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.

research Susceptibility variants for male-pattern baldness on chromosome 20p11

140 citations , October 2008 in “Nature Genetics”

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

32 citations , February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

research Vitamin D-dependent rickets type II. Defective induction of 25-hydroxyvitamin D3-24-hydroxylase by 1,25-dihydroxyvitamin D3 in cultured skin fibroblasts.

81 citations , March 1985 in “Journal of Clinical Investigation”

Measuring 24-OHase induction helps identify defects in vitamin D processing and predict treatment response.

research A gene for monilethrix is closely linked to the type II keratin gene cluster at 12q13

54 citations , January 1995 in “Human Molecular Genetics”

Monilethrix is linked to a gene cluster on chromosome 12.

research Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets due to a Mutation Causing Multiple Defects in Vitamin D Receptor Function

67 citations , August 2004 in “Endocrinology”

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

research Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population

5 citations , January 2016 in “Dermatology”

No significant link between CAG repeat numbers and female pattern hair loss in Han Chinese population.

research A Small Deletion Hotspot in the Type II Keratin GenemK6irs1/Krt2-6gon Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation

53 citations , October 2003 in “Genetics”

The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.

research 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia

1 citations , November 2022 in “Journal of Investigative Dermatology”

ALRN-6924 may prevent hair loss caused by chemotherapy.

research KRT16 wt Allele

February 2020 in “Definitions”

Mutations in the KRT16 gene can cause skin and nail disorders.

research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing

July 2024 in “Journal of Investigative Dermatology”

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases

57 citations , January 2019 in “Stem Cell Research & Therapy”

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

research HtrA1L364P leads to cognitive dysfunction and vascular destruction through TGF‐β/Smad signaling pathway in CARASIL model mice

3 citations , July 2022 in “Brain and Behavior”

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights

December 2025 in “Biomolecules”

Compound 7p shows strong potential as an anticancer agent.

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle

January 2007

research NIPAL4 mutation c.527C˃A identified in Romanian patients with autosomal recessive congenital ichthyosis

1 citations , December 2016 in “Revista română de medicină de laborator”

The NIPAL4 mutation c.527C>A is common in Romanian patients with autosomal recessive congenital ichthyosis.

research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization

22 citations , November 2016 in “International journal of molecular sciences”

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

research A Girl with a Novel Splice Site Mutation in <i>VDR</i> Supports the Role of a Ligand-Independent VDR Function on Hair Cycling

21 citations , January 2006 in “Hormone Research in Paediatrics”

A mutation in the VDR gene affects hair cycling without needing ligand binding.

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