110 citations
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October 2013 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
72 citations
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January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
71 citations
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January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
71 citations
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November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
65 citations
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October 2008 in “Journal of Neuroendocrinology” 55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
50 citations
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May 2020 in “Journal of Clinical Medicine” Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
45 citations
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February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
42 citations
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August 2017 in “Human Reproduction” Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
39 citations
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November 2016 in “Pharmaceutics” The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
36 citations
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May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
34 citations
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February 2016 in “Fertility and Sterility” More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.
34 citations
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October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
31 citations
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March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
27 citations
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February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
23 citations
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March 2019 in “Environmental Chemistry Letters” Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
16 citations
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January 2023 in “Cureus” PCOS in teens causes hormonal imbalances, irregular periods, and can lead to infertility and other health issues.
10 citations
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May 2010 in “Analytica Chimica Acta” New tests detect finasteride and dutasteride in urine quickly and easily.
9 citations
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April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
9 citations
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October 1988 in “Clinics in Dermatology” Hair loss is caused by genetics and hormones, diagnosed through examination and biopsy, and treated with medications or surgery.
8 citations
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March 2020 in “Metabolites” Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
8 citations
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April 1988 in “Journal of endocrinological investigation” Topical spironolactone cream doesn't cause hormone-related side effects in the body.
7 citations
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April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
5 citations
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August 2014 in “Pharmaceutical Development and Technology” Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
3 citations
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March 2021 in “Metabolites” Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
2 citations
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August 2011 in “Revista Medica De Chile” A postmenopausal woman's high testosterone levels and symptoms improved after removing a tumor from her ovary.
1 citations
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April 2021 in “Journal of The American Academy of Dermatology” Some overweight or obese men with long-term frontal fibrosing alopecia may have abnormal sex hormone levels.
November 2025 in “Open Repository of the University of Porto (University of Porto)” Minoxidil and spironolactone can improve hair growth, but responses vary and side effects are common.
November 2025 in “Frontiers in Endocrinology” Apigenin and ellagic acid may help manage PCOS symptoms.