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Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.

Finasteride helps female-pattern hair loss.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Estetrol may help prevent hair loss and promote hair growth in women.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Human hair follicles can process steroid hormones like DHEA.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

The treatment significantly reduced hair growth and male hormone levels in hirsute women.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Testosterone and letrozole treatment speeds up puberty in boys with delayed development.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.

17-beta estradiol and prednisolone may help regrow hair damaged by chemotherapy.

Finasteride effectively reduces DHT and E2 levels, helping with prostate enlargement.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.