November 2020 in “Postepy Dermatologii I Alergologii” Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.
62 citations
,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
55 citations
,
October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
45 citations
,
October 1988 in “British Journal of Clinical Pharmacology” Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
44 citations
,
January 2013 in “International Journal of Trichology” Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.
37 citations
,
May 2016 in “JAAD case reports” Oral minoxidil shows promise in treating monilethrix-related hair loss.
34 citations
,
July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
34 citations
,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
27 citations
,
January 2017 in “Neuropsychopharmacology” The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
25 citations
,
November 2015 in “Journal of Ethnopharmacology” Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
20 citations
,
November 1987 in “Archives of Dermatology” The document concludes that topical minoxidil therapy is safe and effective in promoting hair growth for male pattern baldness.
19 citations
,
January 2016 in “Annals of Dermatology” Dutasteride is safe and effective for treating hair loss, but may decrease libido.
14 citations
,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
13 citations
,
April 2009 in “Acta Medica Scandinavica” Minoxidil lowers blood pressure and causes hair growth, with some side effects.
12 citations
,
March 2017 in “Medicinal Chemistry Research” Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
3 citations
,
October 2015 in “Human Psychopharmacology-clinical and Experimental” Finasteride doesn't affect sleep spindles in men.
14 citations
,
October 1977 in “The Lancet”
13 citations
,
November 2014 in “Pediatric emergency care” Ingesting minoxidil can cause serious heart issues; keep away from children and improve packaging.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
9 citations
,
October 1993 in “The Journal of Clinical Pharmacology” Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
January 2025 in “Editora Acadêmica Periodicojs eBooks” Oral Minoxidil is a practical alternative to Topical Minoxidil for hair loss, but treatment should be personalized.
72 citations
,
December 1983 in “Journal of Investigative Dermatology” Minoxidil helps hair cells live longer and grow longer.
46 citations
,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
7 citations
,
June 2021 in “Cureus” Minoxidil can cause severe body swelling and fluid buildup, which improves after stopping the drug and using diuretics.
25 citations
,
June 2018 in “Clinical and Experimental Dermatology” Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
February 2026 in “Frontiers in Medicine” Oral minoxidil improved hair loss more than oral dutasteride.
23 citations
,
September 2019 in “Journal of The American Academy of Dermatology” Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
24 citations
,
September 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improved or stabilized hair loss in some patients, but higher doses may be needed for significant effects.
16 citations
,
June 2021 in “Journal of Dermatological Treatment” Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.
6 citations
,
May 2020 in “JAMA Ophthalmology” Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.