research Main Plenary Sessions: Summaries of Papers
UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
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research Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor
Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.
research Steroid 5α-reductase inhibition by polymethoxyflavones
Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
research Gonadotrophin-releasing hormone agonist therapy for hirsutism is as effective as high dose cyproterone acetate but results in a longer remission
Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.
research Ethinylestradiol/Chlormadinone Acetate
The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.
research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors
Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
research Anti-androgens for the treatment of hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
research Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls
The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
research Hair Disorders
The document concludes that accurate diagnosis and appropriate management are crucial for treating various hair disorders, which have significant psychological impacts.
research Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Action Mechanism of Chamaecyparis obtusa Oil on Hair Growth
Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Short-term combined treatment with liraglutide and metformin leads to significant weight loss in obese women with polycystic ovary syndrome and previous poor response to metformin
Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
research Recent advances in oxasteroids chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families
Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
research Clinical, metabolic, and endocrine parameters in response to metformin and lifestyle intervention in women with polycystic ovary syndrome: A randomized, double-blind, and placebo control trial
Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
research The SAHA Syndrome
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Management of women with hirsutism in Kosovo
A holistic approach, including medical treatments, lifestyle changes, and mental health support, is crucial for managing hirsutism in women.
research Elevated Free Testosterone Levels in Women With Acne
Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
research Plasmaproteinbindung endogener Glucocorticosteroide und deren Einfluss auf Haar- und Speichelkonzentrationen
Plasma protein binding significantly affects glucocorticosteroid concentration in blood, saliva, and hair.
research PCOS: Perspectives from a Pediatric Endocrinologist and a Pediatric Gynecologist
The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.
research An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma
A new method accurately measures DHEAS in blood, improving on current tests.
research Drug Information Analysis Service
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Antiandrogenic therapy with ciproterone acetate in female patients who suffer from both androgenetic alopecia and acne vulgaris
Ciproterone acetate improves hair regrowth and acne in most female patients.
research Formulasi dan Evaluasi Sediaan Axillary Krim Ekstrak Kunyit (Curcuma longa Linn.) dengan Kombinasi Jahe (Zingiber officinale) sebagai Penghambat Pertumbuhan Bulu pada Aksila
The cream with turmeric and ginger extracts can potentially reduce underarm hair growth effectively.
research Chemical pharmacotherapy options for managing adult acne
The conclusion is that more research is needed to better understand and treat adult acne, and that patient education and simple treatment plans are important for better results.
research Skin Androgen-Related Disorders: Hormonal Treatment
research Die Menopause und ihre Auswirkungen auf Haut und Haare
Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.