40 citations
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January 1994 in “Skin Pharmacology and Physiology” Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” Finasteride improves hair growth in men with androgenetic alopecia.
29 citations
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September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
April 2017 in “Austin Journal of Cancer and Clinical Research” 5α-reductase inhibitors like Finasteride and Dutasteride may help manage prostate cancer by blocking testosterone conversion.
December 2025 in “International Journal of Innovative Technologies in Social Science” Effective treatments for hair loss include minoxidil, 5α-reductase inhibitors, and personalized combination therapies.
December 2023 in “International Journal of Applied Pharmaceutics” Moringa seed oil helped hair growth in rabbits, with the highest dose being most effective.
4 citations
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August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
3 citations
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October 2009 in “Iranian Journal of Basic Medical Sciences” Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.
21 citations
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November 2017 in “Archives of Dermatological Research” Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
2 citations
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September 2022 in “Advances in Environmental Biology” Avicennia marina leaf extract can fight Vancomycin-resistant bacteria.
1 citations
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August 2017 in “Asian Journal of Pharmaceutical and Clinical Research” The 1% ethyl acetate fraction ethosomal gel from Nothopanax scutellarium leaves promotes hair growth but can mildly irritate the skin.
4 citations
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January 2020 in “BioMed Research International” Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.
9 citations
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May 2021 in “Molecules” New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
30 citations
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April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
13 citations
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May 2021 in “Plants” The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.
April 2012 in “KSBB Journal” Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
1 citations
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February 2025 in “South Asian Research Journal of Pharmaceutical Sciences” Eclipta alba flavonoids may help treat diabetes by effectively inhibiting Aldose reductase.
19 citations
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January 2010 in “International Journal of Ayurveda Research” Tectona grandis Linn. seeds extract improved hair growth in mice better than minoxidil.
24 citations
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July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
August 2025 in “Tropical Journal of Natural Product Research” Celery extract and candlenut oil effectively and safely boost hair growth.
4 citations
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April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
4 citations
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May 2019 in “Biology open” Testosterone reduces heart damage and inflammation after injury.
March 2026 in “RS Global journals (RS Global Sp. z O.O.)” Finasteride is effective for hair loss and prostate issues but may cause lasting side effects.
100 citations
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May 2003 in “Journal of Neuroscience” Neuroactive steroids affect cocaine's rewarding effects through the ς1 receptor.
66 citations
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January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
4 citations
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June 2020 in “Processes” Geranium sibiricum may help manage diabetic complications by inhibiting a key enzyme.
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
12 citations
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June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
3 citations
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October 2011 in “QJM” The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
January 2026 in “RSC Advances” Epristeride's metabolism in zebrafish helps improve doping detection methods.