The white wax scale insect's genome shows that complete metamorphosis evolved earlier than thought and highlights differences in male and female development.
305 citations
,
March 2008 in “AJP Endocrinology and Metabolism” SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
41 citations
,
September 2003 in “Journal of Investigative Dermatology” Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.
December 2025 in “Biomolecules” Targeting protein S-palmitoylation could lead to new skin disease treatments.
August 2025 in “Biomolecules” CBD may help with skin and hair issues, but more research is needed.
111 citations
,
April 2023 in “Ultrasonics Sonochemistry” Ultrasound helps efficiently extract beneficial compounds from maidenhairtree for potential medicinal use.
11 citations
,
March 2023 in “Stem Cell Research & Therapy” Epidermal stem cells improve skin graft survival by promoting early blood vessel formation.
10 citations
,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
1 citations
,
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.
3 citations
,
September 2025 in “ChemMedChem” Multitarget drugs are needed to better treat complex diseases.
Plant-derived exosomes show promise for healing skin wounds but need more research and trials.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
298 citations
,
June 2019 in “Marine Drugs” Chitosan is a sustainable, versatile ingredient in cosmetics, enhancing skin hydration and anti-aging while promoting eco-friendly practices.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
128 citations
,
October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
122 citations
,
December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
105 citations
,
December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
92 citations
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December 2020 in “Brain Sciences” Indian herbs like Bacopa monnieri and Centella asiatica may help memory, but more research is needed.
91 citations
,
August 2024 in “Acta Pharmaceutica Sinica B” Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
82 citations
,
May 2020 in “International Journal of Molecular Sciences” Injectable biomaterials can effectively regenerate dental tissues.
80 citations
,
January 2020 in “Journal of Nanobiotechnology” Nanomaterials can aid tissue repair and healing but need more safety research.
78 citations
,
January 2013 in “Dermatology Online Journal” Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.
72 citations
,
November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” Personalized acne treatments and new therapies show promise for better results.
65 citations
,
April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
59 citations
,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
57 citations
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November 2024 in “Aggregate” Smart hydrogels can improve diabetic wound healing by adapting to wound conditions and providing controlled treatment.