research Crystal Structure and Synthesis of 17α-Acetoxy-pregn-4,6-diene-3,20-dione
The compound was successfully made and shows potential for treating prostate cancer.
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690-720 / 1000+ results research Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens
Higher levels of 3α-diol G are linked to more severe female pattern hair loss.
research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2
Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level
Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
research Bottom-up Nanoencapsulation from Single Cells to Tunable and Scalable Cellular Spheroids for Hair Follicle Regeneration
Nanoencapsulation creates adjustable cell clusters for hair growth.
research The tumescent technique facilitates hair micrografting
The tumescent technique improves hair micrografting by providing lasting anesthesia, reducing bleeding, and increasing patient comfort.
research Fractional non-ablative laser-assisted drug delivery leads to improvement in male and female pattern hair loss
Laser-assisted drug delivery improves hair loss.
research Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence
5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
research 5α-Reductase inhibitors in men aged 50 years or older with androgenetic alopecia: A retrospective study
5ARI treatment improves hair growth in older men with minimal side effects.
research Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
PRP injections effectively promote hair growth in androgenetic alopecia patients.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Association of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study
Hair loss linked to prostate enlargement; stress and family history important factors.
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research PCOS and Obesity: Contraception Challenges
Low-dose ethinyl estradiol and LNG-IUD are safer contraception options for obese women with PCOS.
research Surgical Hairline Advancement: Patient Candidacy and Best Techniques
SHA lowers the hairline quickly and patients are usually happy with the results if they are good candidates.
research 5α-Reductase Inhibitors and Chemoprevention: The PCPT and Beyond
5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.
research Primary Cicatricial Alopecia Successfully Treated with A Combination of Oral Zinc with Nd: YAG Laser. A Case Series of Five Patients
Oral zinc and Nd:YAG laser therapy effectively treated primary cicatricial alopecia in five patients.
research Progress in Diagnosis and Treatment of Polycystic Ovary Syndrome with Traditional Chinese and Western Medicine
Combining Traditional Chinese Medicine and Western medicine can improve symptoms, hormone levels, and pregnancy outcomes in Polycystic Ovary Syndrome patients, but more research is needed.
research INDRALUPTA (ALOPECIA AREATA) MANAGEMENT BY PRACCHANA AND CUPPING: A SUCCESS STORY
A man regrew hair in 15 days using Pracchana and cupping therapy.
research Female Progressive Scalp Hair Loss Associated with Ovarian Thecoma
A woman's hair loss was linked to a rare hormone-secreting ovarian tumor, treated with surgery and hair loss medication.
research Síndrome dos ovários policísticos: correlação dos fenótipos com as manifestações metabólicas
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator
The film-trigger applicator improves microneedle skin delivery and drug efficiency using simple finger force.
research Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model
Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
research Hirsutism
Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.