research Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice
Dutasteride works better than finasteride for preventing and treating prostate cancer.
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research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research A Novel Follicular Unit Excision Device for All-Purpose Hair Graft Harvesting
The new hair graft device is faster, more efficient, and reduces damage to hair follicles.
research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
research Assessing dutasteride-associated sexual dysfunction using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells
Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
research Androgenic alopecia may have evolved to protect men from prostate cancer by increasing skin exposure to ultraviolet radiation
Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
research Effects of Exercise Combined with Finasteride on Hormone and Ovarian Function in Polycystic Ovary Syndrome Rats
Exercise and finasteride together improve ovary health in PCOS rats.
research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells
Garden cress extract may help treat skin inflammation and androgen-related disorders.
research Effect of Citrullus colocynthis Schard on Testosterone-Induced Benign Prostatic Hyperplasia
Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
research Relative binding affinity of novel steroids to androgen receptors in hamster prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway
Cepharanthine can potentially treat gastric cancer by stopping tumor growth.
research Origanum vulgareL. leaves extract alleviates testis and sperm damages induced by finasteride: Biochemical, Immunohistological and apoptosis genes based evidences
Oregano extract helps fix testis and sperm damage caused by finasteride.
research “Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women”
Miliacin with polar lipids helps hair growth and improves hair loss in women.
research Bladder cancer survival in men using 5-alpha-reductase inhibitors
Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.
research Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome
Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.
research CD4 expression controls epidermal stem cell balance
CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
research Mucosal TLR5 activation controls healthspan and longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research TLR2 regulates hair follicle cycle and regeneration via BMP signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Effect of alpha-tocopheryl acetate, retinyl palmitate, and phytantriol on hair protection
TRP-hair essence protects hair from heat damage, maintains color, and strengthens hair.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Androgen replacement therapy in women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Treatment of hyperandrogenism in polycystic ovary syndrome
Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
research M5 isolation method preserves higher trichogenic identity and proliferative capacity of human dermal papilla cells
The M5 method is best for isolating cells that help hair growth.
research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research THBS4 promotes hair regeneration by inducing dermal mechanical niche adaptation
THBS4 helps hair grow by activating hair follicle stem cells.
research Dendrobium officinale polysaccharide improves hair regrowth in androgenetic alopecia mice and is associated with coordinated changes in local steroid metabolism, ESR1 activation, and keratin-related follicular responses
Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.
research Health consequences of anabolic steroids: a sexual-medicine perspective
Anabolic steroid abuse can cause sexual, fertility, and health problems.
research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure can slow aging in mice by improving fat metabolism.