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Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

A genetic hair protein variant is more common in Japanese people and is inherited.

Human hair proteins, especially keratins, can protect cells from oxidative stress in lab settings.

PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.

PPARs help regulate skin health and could be used to treat skin disorders.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

DK peptides can reduce hair loss by inhibiting the 5α-reductase enzyme and have antioxidant effects.

Elf5 controls skin cell growth and development, making it a potential target for skin treatments.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.

Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.

Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.

ELF5 is essential for skin cell growth and maintenance.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Type II porcine hair keratin supports cell growth but hinders cell differentiation.

The Fas/FasL pathway may play a role in alopecia areata.