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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

MOF controls skin development by regulating genes for mitochondria and cilia.

Elf5 is important for skin stem cell growth and could help treat skin and hair problems.

Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

ELF5 is essential for skin cell growth and maintenance.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

CCL5 is important for the hair growth potential of human dermal papilla cells.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Human adrenals and gonads have a unique enzyme for steroid hormone production.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

Different enzymes are active in different parts of developing mouse organs.

MLO proteins help regulate calcium and ROS levels, promoting root hair growth in Arabidopsis.

Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.

ARHGEF3 is essential for proper hair follicle development in mice.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

PADI4 enzyme slows down cell growth in developing hair follicles.

HOXC13 is crucial for regulating hair keratin genes in hair follicles.

MEX3A is crucial for maintaining intestinal stem cells in mice.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

5α-reductases increase epitestosterone's effect on androgen receptors.