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Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

The new method makes finasteride cheaper and easier to produce.

Clascoterone is safe for the heart, even at high doses.

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.

A reliable method was developed to measure aristolochic acid-I in rat blood.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.

Low-dose finasteride may increase erectile dysfunction risk over time.

Testosterone affects hair loss, acne, and excessive hair growth, and antiandrogens can help treat these conditions.

Docetaxel slightly extends prostate cancer survival but has significant side effects and high cost.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride safely lowers DHT levels without affecting testosterone.

A reliable method was developed to measure Finasteride and Tadalafil together, showing they degrade under certain conditions.

5α-Reductase inhibitors, like finasteride, can cause serious, persistent side effects not always listed in official drug information.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Methylation in specific gene region causes finasteride resistance in some BPH patients.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

A rare ovarian tumor caused high male hormone levels, but surgery fixed it.

New treatments for male hypogonadism are effective and should be personalized.