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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.

Many black market drugs for bodybuilders are fake and mislabeled.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

The method accurately measures testosterone metabolites with high sensitivity and low environmental impact.

Muscles can make their own androgens, which may help muscle growth.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

TH07 effectively promotes hair regrowth in androgenic alopecia with high patient satisfaction and no major side effects.

Testosterone reduces knee movement, while flutamide and finasteride increase it.

New steroids were effective in blocking male hormone receptors in hamster prostates.

SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.

The method effectively measures drug impact on DHT levels in prostate treatments.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.