research SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion
SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
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660-690 / 1000+ resultsresearch SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism
Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.
research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating
Krt15+ cells in the mouse intestine resist radiation and can start tumors.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Monotherapy for Alopecia Areata: A Systematic Review and Network Meta-Analysis
Intralesional corticosteroids work best for mild alopecia areata, and DPCP works best for moderate to severe cases.
research Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages
Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
research The Relative Efficacy and Safety of Monotherapies for Alopecia Areata: A Network Meta‐Analysis Study
Janus kinase inhibitors are effective and safe for treating Alopecia Areata.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Role of Nanomaterials in Cosmeceuticals: Challenges, Development Strategies, and Future Perspective
Nanotechnology can make cosmetics more effective for skin issues.
research Human Liver MSCs Retain Their Basic Cellular Properties in Chronically Inflamed Liver Tissue
Liver stem cells keep their basic functions even in inflamed liver tissue.
research The relative efficacy of monotherapy with Janus kinase inhibitors, dupilumab and apremilast in adults with alopecia areata: Network meta‐analyses of clinical trials
JAK inhibitors are more effective and safer for treating alopecia areata than dupilumab and apremilast.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATPChannel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
research Biomaterials for dermal substitutes
The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
research Promises and Pitfalls of Regenerative Therapies for Androgenetic Alopecia: Platelet-Rich Plasma, Photobiomodulation, Stem Cells, and Exosomes
Regenerative therapies show promise for hair regrowth, but more research and standardization are needed.
research Relative Efficacy of Conventional Monotherapies and Select Nonconventional, Over‐the‐Counter Products for Male Androgenetic Alopecia: A Network Meta‐Analysis Study
Conventional treatments like dutasteride and minoxidil are effective for male hair loss, with some alternative treatments also showing promise.
research Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury
Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.
research Skin Microbiome Shifts in Various Dermatological Conditions
Skin diseases alter the skin's microbiome, and prebiotic treatments might help.
research Comparative Effect of Conventional and Non-Conventional Over-the-Counter Treatments for Male Androgenetic Alopecia: A Network Meta-Analysis Study
Topical minoxidil 5% is the most effective over-the-counter treatment for male hair loss.
research Comparative Efficacy of Minoxidil and 5‐Alpha Reductase Inhibitors Monotherapy for Male Pattern Hair Loss: Network Meta‐Analysis Study of Current Empirical Evidence
Dutasteride 0.5 mg/day is the most effective treatment for male pattern hair loss.
research Examining the Relationship Between Alopecia Areata and Mental Health: An Investigation of the Global Burden of Disease Study 2021
Alopecia areata is linked to higher anxiety and depression, especially in younger women in certain countries.
research Finasteride Use: Evaluation of Depression and Suicide Risk
Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
research Lasers for treatment of androgenetic alopecia: an in-depth analysis
Laser therapy shows promise for hair loss but lacks strong evidence due to limited studies.
research Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet‐Rich Plasma: A Literature Review
Exosomes from platelet-rich plasma may help heal wounds but need more research for hair growth and skin use.
research Low‐Dose Oral Minoxidil and Associated Adverse Events: Analyses of the FDA Adverse Event Reporting System (FAERS ) With a Focus on Pericardial Effusions
Low-dose oral minoxidil can cause serious side effects like heart issues, so use the lowest effective dose.
research A linear and reticulate crusted keratotic papulopustular eruption: a rare presentation of PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) complex
A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.
research Optimization of Bear Oil Extraction Process and Hair Growth Activity
Enzymatically extracted bear oil has more unsaturated fats and significantly increases hair growth in mice.
research Systematic review of mesotherapy: a novel avenue for the treatment of hair loss
Mesotherapy might improve hair growth, but more research is needed to confirm its safety and effectiveness.
research Secondary amenorrhoea with absent axillary hair
The patient's long-term symptoms were due to Sheehan's syndrome, which improved with hormone therapy.
research Low-Dose Oral Minoxidil for Alopecia: A Comprehensive Review
Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.