March 2026 in “Pigment Cell & Melanoma Research” Clear documentation and shared best practices are essential for improving research consistency in pigment cells.
4 citations
,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
January 2025 in “Frontiers in Medicine” Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
344 citations
,
June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
18 citations
,
October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
January 2019 in “Our Dermatology Online” Almost 40% of older men in the study had hair loss on the front and side of their legs, and most were unaware of it.
September 2012 in “British Small Animal Veterinary Association eBooks” The document concludes that pigmentation disorders in animals involve complex interactions between melanocytes and keratinocytes.
October 2021 in “QJM: An International Journal of Medicine” Vitiligo patients have higher hydrogen peroxide levels and lower E-cadherin, affecting skin cell adhesion and pigmentation.
139 citations
,
October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
37 citations
,
October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
6 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.
March 2026 in “International Journal of Innovative Technologies in Social Science” Vitiligo is a systemic disease with psychological effects, and new treatments focus on personalized care.
29 citations
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January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
21 citations
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December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
17 citations
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April 2023 in “ACS Biomaterials Science & Engineering” Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
5 citations
,
May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
August 2025 in “Annals of Medicine” Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
12 citations
,
October 2023 in “International Journal of Molecular Sciences” Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.
12 citations
,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
1 citations
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September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
March 2026 in “Preprints.org” Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
October 2025 in “Journal of Investigative Dermatology” Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
13 citations
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September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
20 citations
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October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Follicular unit extraction can effectively treat a specific type of vitiligo.
1 citations
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June 2024 in “International Journal of Clinical & Experimental Dermatology” Surgery can help treat vitiligo when other treatments don't work.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.