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research 0935 Unravelling the role of JAK3/TEC kinase signalling with ritlecitinib in alopecia areata lesional skin and alopecia areata-induced human hair follicles ex vivo

July 2025 in “Journal of Investigative Dermatology”

Ritlecitinib reduces alopecia areata symptoms by blocking JAK3/TEC signaling and T-cell activity.

research UT-018 Accelerates Wound Repair and Hair Follicle Regeneration in Murine Models

1 citations , May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

UT-018 speeds up wound healing and boosts hair growth in mice.

research Nano-PROTACs: state of the art and perspectives

51 citations , January 2024 in “Nanoscale”

Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.

research Arsenic Trioxide as Effective Therapy for Relapsed Acute Promyelocytic Leukemia

22 citations , November 2002 in “Clinical journal of oncology nursing”

Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.

research Efficacy and Safety of Ritlecitinib in the Asian Subpopulation of the ALLEGRO ‐2b/3 and ALLEGRO ‐ LT Clinical Studies for Alopecia Areata

February 2026 in “The Journal of Dermatology”

Ritlecitinib effectively regrows scalp, eyebrow, and eyelash hair in Asians with alopecia areata and is safe.

research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

12 citations , December 2011 in “Journal of Dermatological Science”

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

A Counter Gradient of Activin A and Follistatin Instructs the Timing of Hair Cell Differentiation in the Murine Cochlea

research Decision letter: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

May 2019

Activin A promotes ear hair cell development, while follistatin delays it.

research 4 Anti-androgens in gynaecological practice

7 citations , September 1988 in “Baillière's clinical obstetrics and gynaecology”

Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.

research The AhR pathway is dysregulated in alopecia areata

2 citations , March 2025 in “Journal of Translational Autoimmunity”

Targeting the AhR pathway may help treat alopecia areata.

research The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity

January 2018 in “Stem cell biology and regenerative medicine”

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

130 citations , February 2018 in “Journal of Investigative Dermatology”

Tofacitinib may help treat severe hair loss, but more research is needed.

research Periocular Manifestations of Afatinib Therapy

6 citations , December 2018 in “Ophthalmic Plastic and Reconstructive Surgery”

Afatinib can cause eyelash and eyebrow issues, leading to eye irritation and pain.

research Real‐World Efficacy and Safety of Tofacitinib for Patients With Alopecia Areata: A Retrospective Multi‐Center Cohort Study

April 2026 in “Clinical and Translational Science”

Tofacitinib effectively treats severe alopecia areata, improving hair regrowth and patient satisfaction.

research Atrichia with papular lesions in a Taiwanese patient without hairless (HR) gene mutation

3 citations , March 2010 in “Dermatologica Sinica”

A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.

research AcD : A Novel Bioactive Polymer Scaffold of Adipose‐Derived Stem Cells Combining With Decellularized Extracellular Matrix in Tissue Engineering

August 2025 in “Journal of Polymer Science”

AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.

research Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers

70 citations , April 2016 in “Experimental Dermatology”

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

research DEEP REINFORCEMENT LEARNING FOR SCALABLE CONTROL OF BOOLEAN MODELS IN THE CONTEXT OF CELLULAR REPROGRAMMING

January 2024 in “Wiadomości Lekarskie”

pbn-STAC effectively finds strategies for cellular reprogramming using deep reinforcement learning.

research Baricitinib Provides Higher Efficacy in Adolescents Relative to Adults With Alopecia Areata Despite More Severe Disease at Baseline: 36-Week Outcomes From BRAVE-AA Trials

November 2025 in “SKIN The Journal of Cutaneous Medicine”

The study found that Baricitinib (Bari), a Janus kinase inhibitor, is effective and safe for treating severe alopecia areata (AA) in both adolescents and adults. In the BRAVE-AA trials, 257 adolescents and 1,200 adults were treated with either Bari 4mg, Bari 2mg, or a placebo. At 36 weeks, 42.4% of adolescents on Bari 4mg achieved a SALT score of less than 20, compared to 34% of adults. Adolescents showed higher response rates despite having more severe disease at baseline, indicating the potential benefits of early intervention. Common side effects included headache, acne, and upper respiratory tract infections.

research SUN-911 Immunotherapy Use in Adrenocortical Carcinoma with Encouraging Results- a Case Report

1 citations , April 2020 in “Journal of the Endocrine Society”

Immunotherapy with pembrolizumab significantly reduced cancer in a young woman with adrenocortical carcinoma.

research 054 Deep Analysis of CD4+ Trm Cells in Normal and Atopic Dermatitis Human Skin

November 2025 in “Journal of Investigative Dermatology”

Certain immune cells in atopic dermatitis skin could be targeted for treatment.

Real-World Experience of Tofacitinib and Baricitinib Use in Alopecia Areata in Greek Population: A Retrospective Analysis with Focus on Safety

research Real-World Experience of Tofacitinib and Baricitinib Use in Alopecia Areata in Greek Population: A Retrospective Analysis With Focus on Safety

2 citations , April 2024 in “Dermatology Practical & Conceptual”

Tofacitinib and baricitinib are effective and safe for treating severe alopecia areata, especially in younger people.

research Upadacitinib for management of alopecia areata and rheumatoid arthritis: Letter to the editor

April 2024 in “JEADV clinical practice”

Upadacitinib significantly improved both rheumatoid arthritis and alopecia areata in a patient.

research Synthesis and biological activity of raltitrexed-carrier conjugates.

2 citations , March 2010 in “Acta Biochimica Polonica”

Raltitrexed conjugates are less potent than the free drug but more effective at high concentrations.

Response to Baricitinib in the Treatment of Patients with Early and Late Onset Alopecia Areata in the Phase 2 Portion of BRAVE-AA1 Randomized Controlled Trial

research 27604 Response to baricitinib in the treatment of patients with early and late onset alopecia areata in the phase 2 portion of BRAVE-AA1 randomized controlled trial

1 citations , August 2021 in “Journal of The American Academy of Dermatology”

Baricitinib was effective in treating both early and late onset alopecia areata.

research Postzygotic Mutations in Beta-Actin Are Associated with Becker’s Nevus and Becker’s Nevus Syndrome

62 citations , March 2017 in “Journal of Investigative Dermatology”

Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.

Steroid-Free Monotherapy with Tofacitinib in Severe Therapy-Resistant Alopecia: A Retrospective Analysis

research A Real-World Study of Steroid-Free Monotherapy with Tofacitinib in Severe and Therapy-Recalcitrant Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Cases: A Retrospective Analysis

November 2023 in “Indian Dermatology Online Journal”

Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.

research Extracellular ATP in Plants. Visualization, Localization, and Analysis of Physiological Significance in Growth and Signaling

248 citations , September 2006 in “PLANT PHYSIOLOGY”

Extracellular ATP is crucial for plant root growth and signaling.

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