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630-660 / 1000+ resultsresearch Author response: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
research 848 Genes implicated in lipid & metabolic regulation downregulated in CCCA
848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.
research ADAM17 variant causes hair loss via ubiquitin ligase TRIM47 mediated degradation
A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.
research Co-expression of PADI isoforms during progenitor differentiation enables functional diversity
Different PADI isoforms help cells develop diverse functions.
research Phosphatidylinositol 3-Kinase/Akt-Dependent and -Independent Protection Against Apoptosis in Normal Human Melanocytes
Normal human melanocytes can avoid cell death through multiple pathways.
research Hair growth stimulated by allogenic adipose-derived stem cells supplemented with ATP in a mouse model of dihydrotestosterone-induced androgenetic alopecia
Combining stem cells with ATP significantly boosts hair regrowth in mice with hair loss.
research The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles
PADI4 enzyme slows down cell growth in developing hair follicles.
research Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome
Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
research Morphogenesis- and Hair Cycle-dependent Expression of Trichohyalin, Peptidylarginine Deiminase Type III and Deiminated Trichohyalin in Rat Dorsal Skin Hair Follicles
THH and PAD type III appear together early in hair growth, but deiminated THH appears later, suggesting another factor is involved.
research IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.
research TLRgeting Evasion of Immune Pathways in Glioblastoma
Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
research Peptidylarginine Deiminase Isoforms Are Differentially Expressed in the Anagen Hair Follicles and Other Human Skin Appendages
PAD enzymes play a key role in hair growth and structure.
research From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy
The HATMSC1 cell line from fat tissue can produce helpful factors for regenerative and immune therapies.
research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes
CRH promotes fat production in skin cells, affecting conditions like acne.
research Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation
Hair growth genes work better with more glucose due to changes in gene-regulating markers.
research Epimorphin and Epithelial Morphogenesis
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
research Very-long-chain Acyl-CoA Synthetases
Very-long-chain acyl-CoA synthetases and fatty acid transport proteins play key roles in fatty acid metabolism and lipid processing in different tissues.
research Atopinio dermatito sąsaja su metaboliniu sindromu
Atopic dermatitis is linked to obesity, especially in severe cases.
research Increased PHGDH expression promotes aberrant melanin accumulation
Higher PHGDH levels cause unusual melanin buildup in hair follicles.
research 0952 Spatial transcriptomics reveal compartmentalized dysregulation of lipid metabolism in acne vulgaris
Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.
research 331 Mitochondrial stress contributes to atopic dermatitis
Mitochondrial stress can lead to atopic dermatitis.
research Lipid droplets and associated proteins in sebocytes
Sebum from sebocytes is important for skin health and linked to conditions like acne and hair loss.
research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research Hormone-induced aberrations in electromagnetic adhesion signaling as a developmental factor of androgenetic alopecia
Hormones cause hair loss by affecting cell growth and weakening cell attraction.
research Comparative transcriptome profiling provides new insights into mechanisms of androgenetic alopecia progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
research Anais Congresso Nacional Sobre Obesidade e Síndrome Metabólica
Obesity can cause acne in kids and teens due to hormonal and metabolic changes.
research Hair follicle neogenesis in adult skin
research Steroidogenesis of the testis – new genes and pathways
New genes and pathways are important for testosterone production and male sexual development.