research Exploring the Gut Microbiome and Metabolome in Individuals with Alopecia Areata Disease
Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.
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research Comparative proteomic analysis of male and female androgenetic alopecia: elucidating gender-specific molecular patterns
Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.
research Assessment of Serum Level of Myostatin in Patients with Androgenetic Alopecia and its Relation to Insulin Resistance
Higher myostatin and insulin resistance are linked to androgenetic alopecia.
research L-Ornithine ketoacid-transaminase assay in hair roots of homozygotes and heterozygotes for gyrate atrophy
research Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese
research Insulin Resistance in Patients with Androgenic Alpoecia”
Insulin resistance may contribute to hair loss in people with androgenic alopecia.
research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model
IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.
research Selective JAK 1 inhibition with upadacitinib as a potential treatment for coexistent severe atopic dermatitis and alopecia areata
research Upadacitinib in concurrent Crohn's disease, atopic dermatitis and alopecia areata: A case report
Upadacitinib improved Crohn's disease, atopic dermatitis, and alopecia areata in one patient.
research Normoglycemia and type 2 diabetes: exploring secreted frizzled-4, insulin resistance, and waist-height ratio
Higher SFRP-4 levels were found in people without a diabetic family history.
research A prospective study of the prevalence of clear-cut endocrine disorders and polycystic ovaries in 350 patients presenting with hirsutism or androgenic alopecia
Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.
research Evaluation of the serum C‐reactive protein–albumin ratio and its relationship with disease severity IN alopecia areata: A prospective case–control study
CAR is a useful marker for assessing alopecia areata severity.
research Androgenetic Alopecia and Metabolic Syndrome: Is Alarin a Missing Link?
Higher alarin levels might link hair loss and metabolic syndrome.
research Age-related changes in endogenous glucocorticoids, gonadal steroids, endocannabinoids and their ratios in plasma and hair from the male C57BL/6 mice
Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
research 570 Targeting phosphodiesterase 8A (PDE8A) to boost adipogenesis and hair regeneration
Inhibiting PDE8A may help treat hair loss by boosting fat cell growth and hair regeneration.
research Cortisol levels in atypical and non-atypical depression using hair and saliva specimens
research 498 A Multi-Omics Approach to create a Human Hair Atlas for healthy and AGA models
The research aims to better understand hair follicle regulation and find new treatments for hair loss.
research Mécanismes moléculaires et cellulaires des processus de différenciation et de plasticité cellulaire pour la formation des adipocytes
EGM2 and SOX2 help form beige adipocytes by maintaining ASC immaturity and activating brown adipocytes.
research Skin Manifestations of Insulin Resistance: From a Biochemical Stance to a Clinical Diagnosis and Management
Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
research Successful treatment with upadacitinib in concurrent atopic dermatitis, Crohn’s disease, alopecia areata, and eosinophilic gastropathy in a pediatric patient
Upadacitinib improved symptoms and hair regrowth in a teen with multiple autoimmune conditions.
research Serum anti-Müllerian hormone as a predictor of polycystic ovarian syndrome among women of reproductive age
High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.
research Co‐regulatory mechanisms and potential markers of oxidative stress‐related genes in vitiligo and alopecia areata
KLB and EIF3C genes are key for early diagnosis of vitiligo and alopecia areata.
research Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
research Increased androgen bioavailability is associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome
Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
research Diagnosis of childhood and adolescent growth hormone deficiency using transcriptomic data
Childhood growth hormone deficiency can be accurately diagnosed using gene expression data and random forest analysis.
research Association of ACE2, Insulin Resistance, and Other Parameters in Obese Polycystic Ovary Syndrome Patients Infected with COVID-19
PCOS women with COVID-19 have higher cardiometabolic risks.
research Conjoint analysis of methylation, transcriptomic, and proteomic profiles in pemphigus vulgaris
Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.
research Sudden improvement of alopecia universalis and psoriatic arthritis while receiving upadacitinib: a case-based review
Upadacitinib significantly improved alopecia universalis and psoriatic arthritis in a patient.
research Efficacy of 0.1% adapalene in a non-inflammatory Kyoto Rhino Rat acne model
Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.
research Polycystic ovary syndrome — the skin as a mirror of endocrine disorders
Polycystic ovary syndrome (PCOS) is a complex disorder characterized by hormonal and metabolic dysregulation, with dermatological manifestations often serving as early indicators. This review highlights that the majority of PCOS patients experience skin-related symptoms, with hirsutism affecting about 70% of women, correlating with androgen levels and BMI. Androgenic acne is present in around 40% of patients, while androgenic alopecia affects 5–15%. Acanthosis nigricans is also noted, though its prevalence is less defined. The skin effectively reflects hormonal imbalances in PCOS, aiding in diagnosis and treatment.