64 citations
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March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
62 citations
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January 2015 in “Journal of Dermatological Science” New genetic discoveries may lead to better treatments for alopecia areata.
60 citations
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November 2023 in “Biology” Aging skin causes inflammation that affects the whole body.
54 citations
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May 2015 in “Endocrinology” Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.
52 citations
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April 2008 in “Therapeutics and clinical risk management” The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.
51 citations
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December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
50 citations
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January 2014 in “PLOS ONE” Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
45 citations
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May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
38 citations
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January 2020 in “Cell Transplantation” Targeting ACE2 and TMPRSS2 may help prevent or treat COVID-19 in cancer patients.
35 citations
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January 2024 in “BioMolecular Concepts” Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
30 citations
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July 2023 in “Journal of Cutaneous Medicine and Surgery” Understanding sex and gender differences can improve personalized dermatology care.
28 citations
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January 2017 in “Indian Dermatology Online Journal” Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.
26 citations
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April 2023 in “Medicina” Platelet-rich plasma therapy improves oral lichen planus symptoms with few side effects.
26 citations
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December 2020 in “International Journal of Molecular Sciences” Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
25 citations
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January 2024 in “Journal of Lipids” Cubosomes improve drug delivery for skin and eye diseases by enhancing adhesion, retention, and release.
22 citations
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January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
21 citations
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December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
20 citations
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April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
20 citations
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February 2021 in “Frontiers in Pharmacology” Angelica sinensis and Tetrapanax papyrifer are common in Taiwanese TCM for lactation, with potential anticancer benefits.
20 citations
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December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
19 citations
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May 2016 in “Biology Direct” A new method, iSiMPRe, effectively identifies key protein regions in cancer genes, highlighting potential drug targets.
18 citations
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July 2024 in “Frontiers in Immunology” Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
16 citations
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November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
16 citations
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January 2019 in “Pharmaceutical biology” Lespedeza cuneata extract may help treat enlarged prostate.
16 citations
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April 2018 in “Current opinion in gynecology and obstetrics” Hispanic women with PCOS are more likely to have liver diseases like NAFLD and NASH.
15 citations
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July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
15 citations
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January 2020 in “ILAR Journal” Nonhuman primates are valuable in research but their natural health variations can complicate study results.