344 citations
,
June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
23 citations
,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
66 citations
,
July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
30 citations
,
March 2008 in “Wound Repair and Regeneration” Estrogen affects scalp cell types differently, enhancing some wound healing processes.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
38 citations
,
April 2005 in “Journal of Investigative Dermatology” Human hair follicle cells can become fat and bone cells, useful for therapy.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
23 citations
,
May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
37 citations
,
December 2001 in “Journal of Investigative Dermatology” Leptin may play a role in hair growth and hair follicle health.
1 citations
,
February 2025 in “International Journal of Molecular Sciences” Enzymatic digestion is an efficient method for isolating cells from hair follicles for tissue-engineered skin.
16 citations
,
July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
August 2025 in “Stem Cell Research & Therapy” Exosomes from stem cells can help regrow hair better than minoxidil.
120 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
107 citations
,
December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
29 citations
,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
9 citations
,
May 2010 in “Journal of Investigative Dermatology” Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.
1 citations
,
November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.
86 citations
,
May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
12 citations
,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
1 citations
,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
78 citations
,
August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
1 citations
,
July 2025 in “Stem Cell Research & Therapy” Stem cell technology may improve hair loss treatments by providing more effective and personalized options.
13 citations
,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
November 2024 in “Stem Cell Research & Therapy” A new method improves the isolation of hair follicle cells for better hair growth research.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
30 citations
,
September 2000 in “Journal of Dermatological Science” Fatty acid composition in human skin, mouth, and hair cells varies with keratinization, and cultured cells show essential fatty acid deficiency.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.