18 citations
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January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
30 citations
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June 2017 in “Current stem cell research & therapy” Adipose-derived stem cells (fat cells) show promise in treating hair loss in both men and women.
January 2008 in “Di-san junyi daxue xuebao” Rat hair follicle stem cells can become corneal epithelium-like cells when exposed to rabbit corneal limbal stroma.
November 2025 in “Journal of Investigative Dermatology” Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
28 citations
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October 1984 in “Journal of Investigative Dermatology”
80 citations
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June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
13 citations
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February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
48 citations
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March 2020 in “Stem Cell Research & Therapy” Using a collagen sponge scaffold helps stem cells become more like skin cells.
34 citations
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February 2012 in “American Journal of Dermatopathology” Calretinin can help identify certain skin structures and tumors.
Wnt7a helps corneal cells grow and stick together, aiding in repair.
36 citations
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January 1994 in “Cell and Tissue Research” 9 citations
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September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
January 2007 in “Jiepouxue yanjiu” ES cell-derived stem cells can help regenerate skin and form gland-like structures.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
April 2017 in “Journal of Investigative Dermatology” Dermal lymphatic vessels help hair growth by affecting hair cycle phases.
1 citations
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January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
July 2025 in “Journal of Investigative Dermatology” TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
5 citations
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March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
11 citations
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June 2005 in “Stem Cells and Development” Intestinal stem cells can help repair skin damage from radiation.
6 citations
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January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.
April 2016 in “Journal of Investigative Dermatology” A specific type of immune cells, called CD301b-expressing macrophages, are crucial for skin repair processes.
18 citations
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May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
5 citations
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February 2022 in “International Journal of Molecular Sciences” Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
48 citations
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May 2002 in “Journal of Anatomy” VEGFs increase blood vessel permeability, especially in diseases like cancer and heart disease.
482 citations
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June 1979 in “Proceedings of the National Academy of Sciences” Keratins provide structural strength in epithelial cells and help identify cell origins.
Skin stem cells in hair follicles are important for touch sensation.
116 citations
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August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
5 citations
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October 2024 in “Molecules and Cells” Epidermal stem cells work with the skin's environment to heal wounds effectively.
March 2024 in “Bioactive Materials” New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.