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Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups During the First Hair Cycle

research 2063-LB: Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups during the First Hair Cycle

June 2024 in “Diabetes”

Erythropoietin overexpression disrupts hair growth and fat formation in mice.

research In Vivo Evaluation ofEclipta albaExtract as Anticancer and Multidrug Resistance Reversal Agent

9 citations , June 2014 in “Nutrition and Cancer”

Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.

research Uncombable hair syndrome due to maternal uniparental disomy of chromosome 1

December 2022 in “American journal of medical genetics. Part A”

A person got uncombable hair syndrome from two copies of chromosome 1 from their mother.

research HMGB1 promotes hair growth via the modulation of prostaglandin metabolism

12 citations , April 2019 in “Scientific Reports”

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs

34 citations , August 2016 in “Scientific Reports”

Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.

Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata

research Increased retinol‐binding protein (RBP) 4 and anti‐RBP4 antibody in alopecia areata

6 citations , June 2011 in “British Journal of Dermatology”

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss

688 citations , June 2007 in “Cell Stem Cell”

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

research Dermal EZH2 simultaneously orchestrates dermal differentiation and epidermal proliferation during murine skin development

November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dermal EZH2 controls skin cell growth and differentiation in mice.

research Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia

74 citations , October 2012 in “The American Journal of Human Genetics”

Mutations in the HOXC13 gene cause hair and nail development issues.

research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells

8 citations , June 2001 in “Journal of Biological Chemistry”

A truncated protein linked to breast cancer may change cell adhesion.

research Differential expression of KRT83 regulated by the transcript factor CAP1 in Chinese Tan sheep

5 citations , March 2017 in “Gene”

CAP1 decreases the expression of a hair-related protein in young Tan sheep's skin.

research Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells

July 2008 in “VTechWorks (Virginia Tech)”

PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.

Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin During Hair Follicle Development

research Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development

2 citations , February 2014 in “Animal Biotechnology”

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

research The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation

March 2026 in “Adipocyte”

Spt4 and Spt6 are essential for fat cell development.

research Lamins in development, tissue maintenance and stress

64 citations , November 2012 in “EMBO reports”

Lamins are vital for cell survival, organ development, and preventing premature aging.

research MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

1 citations , July 2023 in “Nature communications”

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

research The first broad replication study of SNPs and a pilot genome‐wide association study for androgenetic alopecia in Asian populations

1 citations , June 2022 in “Journal of Cosmetic Dermatology”

Two specific genetic markers increase the risk of hair loss in Asian populations.

research 102 EZH2 is required for human hair follicle growth and epidermal differentiation

August 2016 in “Journal of Investigative Dermatology”

EZH2 is essential for hair growth and skin cell development.

research Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata

48 citations , September 2011 in “British Journal of Dermatology”

Epigenetic changes in blood cells may contribute to alopecia areata.

research The protease corin regulates electrolyte homeostasis in eccrine sweat glands

10 citations , February 2021 in “PLoS biology”

Corin helps control salt and sweat release in sweat glands.

A New Heterozygous Variant of c.1225_1227delTTC (p.Phe409del) in Insulin Receptor Gene Associated with Severe Insulin Resistance and Hyperandrogenemia in an Adolescent Female with Type A Severe Insulin Resistance Syndrome

research A New Heterozygous Variant of c.1225_1227delTTC (p.Phe409del) in Insulin Receptor Gene Associated with Severe Insulin Resistance and Hyperandrogenemia in an Adolescent Female with Type A Severe Insulin Resistance Syndrome

1 citations , November 2024 in “Diabetes Metabolic Syndrome and Obesity”

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

research Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene

January 2022 in “Mammalian Genome”

The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.

research Reply

2 citations , October 2000 in “Journal of Investigative Dermatology”

AUC and APL are distinct conditions needing careful clinical assessment.

research Serum Fatty Acid Binding Protein 4 in Patients with Androgenetic Alopecia

August 2020 in “Benha Journal of Applied Sciences”

Higher FABP4 levels may help diagnose androgenetic alopecia early.

research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient

September 2019 in “Journal of Investigative Dermatology”

PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.

research Atrichia With Papular Lesions

32 citations , May 1986 in “Archives of Dermatology”

The condition is likely inherited in an autosomal-dominant pattern.

research Identification of Potential Hub Genes in Alopecia Areata

4 citations , October 2024 in “Experimental Dermatology”

CD8A and FOXD2-AS1 may be key for diagnosing and treating alopecia areata.

research HR Gene Variants Identified in Mexican Patients with Alopecia Areata

6 citations , April 2023 in “Current Issues in Molecular Biology”

A specific gene variant may increase the risk of developing Alopecia Areata.

research Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle

94 citations , July 2003 in “Journal of biological chemistry/The Journal of biological chemistry”

EGF controls hair growth by regulating hair follicles' growth phases.

research MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters

November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

MOF controls skin development by regulating genes for mitochondria and cilia.

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