research Male pattern androgenetic alopecia in an Indian context: a perspective study
At least 87% of Indian men experience hair loss, with type II being most common and severity increasing with age.
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research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Prevalence of androgenetic alopecia in China: a community-based study in six cities
Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Novel inhibitors of 5α-reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Hair Follicle Classification and Hair Loss Severity Estimation Using Mask R-CNN
An intelligent system can classify hair follicles and measure hair loss severity with reasonable accuracy.
research Age-Induced Hair Graying and Oxidative Stress
research Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland
Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
research Management of Androgenetic Alopecia in Postmenopausal Women
Treat hair loss in postmenopausal women with diet, avoiding certain drugs, and using medications like minoxidil or finasteride.
research Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands
AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.
research Hair Aging Revisited: An Expert Delphi Consensus on Pathogenesis, Clinical Features, and Future Therapies
Experts agree on understanding hair aging to improve diagnosis and treatments.
research Clinical cases of Darier-White follicular dyskeratosis
Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.
research Hair Loss and It’s Homeopathic Approach
Combining trichology and homeopathy is effective for diagnosing and treating hair loss.
research Age-Induced Hair Graying and Oxidative Stress
Gray hair is caused by oxidative stress damaging hair cells.
research Finasteride: Middle-Age Cure-All for Alopecia and Benign Prostatic Hyperplasia?
Finasteride reduces prostate cancer risk but may increase high-grade cancer cases.
research Androgens and alopecia
Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.
research ScalpEye: A Deep Learning-Based Scalp Hair Inspection and Diagnosis System for Scalp Health
ScalpEye accurately diagnoses scalp issues like dandruff and hair loss.
research Prevalence and associated factors of skin diseases in aged nursing home residents: a multicentre prevalence study
Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.
research Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Re-growth in Testosterone-treated Mice
Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
research Skin disorders in elderly subjects
Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.
research Alopecia: unapproved treatments or indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Age-related changes in the dorsal skin histology in Mini and Wistar rats.
Mini rats have thinner skin, more fat, and different hair cycles than Wistar rats due to lower growth hormone levels.
research HAIR MATRIX CELL KINETICS: A SELECTIVE REVIEW
Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research A clinical study of geriatric dermatoses
Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
research Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea
Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
research Top Ten List of Clinical Pearls in the Treatment of Acne Vulgaris
Start acne treatment early to prevent scarring, consider antibiotic resistance, use maintenance therapy, and manage side effects carefully.
research Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasis
iNKT cells help develop and maintain healthy skin in young mice.