December 2024 in “Cell Communication and Signaling” Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.
October 2024 in “Consilium Medicum” Understanding fibroblasts helps improve cosmetic treatments for aging skin.
Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.
January 2017 in “Chemistry & Industry” Eating fewer calories may slow aging and removing old cells can increase lifespan in mice.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
70 citations
,
July 2016 in “Aging” Targeting dermal adipocytes may help combat skin aging.
20 citations
,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
3 citations
,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
July 2007 in “Cancer biology & therapy” Removing a key gene in mice leads to premature aging and loss of stem cells.
49 citations
,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
41 citations
,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
16 citations
,
February 2010 in “Facial Plastic Surgery Clinics of North America” Dr. Samuel M. Lam's article concludes that skilled facial fat grafting can effectively restore facial volume and serve as a complement or alternative to traditional face-lifting methods.
June 2026 in “Journal of Biological Studies” Centella asiatica may help extend healthspan by targeting aging processes.
July 2025 in “Current Stem Cell Research & Therapy” MSC-Exo are safe and effective for treating skin diseases.
Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.
7 citations
,
October 2024 in “Cells” PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
3 citations
,
March 2024 in “iScience” Long-lived proteins may predict age-related diseases.
December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
4 citations
,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
May 2004 in “Archives of Facial Plastic Surgery” The book is a detailed guide on facial rejuvenation techniques and is recommended for new facial plastic surgeons.
April 2025 in “Journal of Skin and Stem Cell” PDRN from trout sperm helps skin and hair regeneration but is costly and complex to produce.
2 citations
,
December 2025 in “Nature Communications” H2AK119ub helps keep hair follicle stem cells in a resting state, preventing early aging.
131 citations
,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
Aging disrupts skin repair and stress responses, but exercise-related IL-15 improves wound healing and skin health in older skin.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
263 citations
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February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.