research Effectiveness of an Autologous Micrografting Technology for Treating Stretch Marks
Autologous micrografting shows promise in effectively treating stretch marks.
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450-480 / 1000+ resultsresearch Response to Pavlović ’s “Response to Li et al.’s ‘Therapeutic efficacy of platelet-rich plasma combining with microneedling and topical minoxidil in refractory severe androgenic alopecia’”
Combining PRP with microneedling and minoxidil may help treat severe hair loss.
research Observation on the Efficacy of a Combined Treatment for Moderate and Severe Androgenetic Alopecia Incorporating Electric Microneedles
The combined treatment for hair loss is effective, easy to use, and has mild side effects.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
This study introduces a finite element analysis (FEA)-guided framework for designing separable bubble microneedles (BMNs) that optimize geometry and cavity parameters for controlled tip separation and robust insertion. The study tested minoxidil sulfate-loaded BMNs (MXS-BMNs) and insulin-loaded BMNs (INS-BMNs) for transdermal and sublingual delivery, respectively. The BMNs demonstrated effective payload release, with over 80% liberated within 10 minutes. In ex vivo tests, MXS-BMNs showed significantly higher minoxidil permeation compared to topical gel, and in vivo tests on mice showed accelerated hair regrowth. INS-BMNs effectively lowered glucose levels in diabetic rats, comparable to subcutaneous injections. This approach reduces empirical iteration, facilitating the development of efficient microneedle systems for rapid drug delivery.
research A study of the efficacy of skin needling and platelet rich plasma in the treatment of androgenetic alopecia
research The efficacy of topical cetirizine using microneedling in androgenetic alopecia male patients
Topical cetirizine with microneedling effectively promotes hair growth in men with androgenetic alopecia.
research Commentary on Micropunch (0.8 mm or Less in Diameter) Hair Transplantation
Small micropunches for hair transplants can increase density but may cause more bleeding and longer healing.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
Bubble microneedles effectively deliver drugs through the skin and mouth, improving treatment speed and efficiency.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells
Recombinant Filaggrin-2 microneedles effectively promote hair growth and repair in hair loss.
research Comparison between isolated Q-switched laser treatment versus association with microneedling on tattoo removal: Case report
Combining microneedling with Q-switched laser treatment for tattoo removal did not improve results and caused more pain.
research Analysis of Trend of Studies on Microneedle Treatment System (MTS)
Microneedle Treatment System is effective for hair growth and skin improvement with no serious side effects, but more research is needed.
research Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma using either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata
Both treatments help hair regrowth, with PRP being slightly better.
research Effect of Microneedling with Growth Factors and Low-Level Light Therapy on Trichotillomania Treatment
The combined therapy of microneedling and light therapy effectively and safely promotes hair regrowth in trichotillomania.
research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research Microneedling with topical administration of bleomycin as a treatment method for plantar warts
Microneedling with bleomycin effectively treats plantar warts with fewer sessions.
research Synergistic delivery of ginseng exosomes and biomimetic melanosomes via temporally controlled hydrogel microneedles restrain the pathologic triad of vitiligo
A new microneedle treatment can effectively repigment skin in vitiligo.
research Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles
A microneedle patch with curcumin and stem cell components effectively treats hypertrophic scars and promotes healing.
research Microneedle-Based Codelivery of Platycladus orientalis -Derived Extracellular Vesicles and Minoxidil Nanoparticles for Androgenetic Alopecia Treatment
A new microneedle treatment combining plant-derived vesicles and minoxidil may improve hair growth for hair loss.
research Ultrasonic Hollow Microneedle Array (USHM) for Androgenetic Alopecia Treatment through Modulating the Expression of Hair-Growth-Associated Genes
Ultrasonic microneedles improve hair regrowth treatment effectiveness without side effects.
research Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment
Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.
research Hydrogel microneedle delivery of a palmitoylated peptide promotes hair regeneration via dual activation of Wnt/β-catenin and cAMP–PKA signaling
The study developed a palmitoylated peptide, Pal-MPAPO, incorporated into a hyaluronic acid-based hydrogel microneedle system for effective transdermal delivery to promote hair regeneration. The microneedles demonstrated sufficient mechanical strength for skin insertion and enabled prolonged release of the peptide. In human dermal papilla cells, Pal-MPAPO activated the Wnt/β-catenin pathway and increased cAMP levels primarily through VPAC1, with no significant role for VPAC2. Molecular interactions were confirmed through various simulations and imaging techniques. In a C57BL/6 mouse model, the Pal-MPAPO-loaded microneedles significantly enhanced hair regrowth, showing similar efficacy to minoxidil but requiring less frequent application. This suggests Pal-MPAPO as a promising candidate for hair regeneration with the hydrogel microneedle system offering a targeted delivery method.
research Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research A Comparative Study on Adipose-Derived Mesenchymal Stem Cells Secretome Delivery Using Microneedling and Fractional CO2 Laser for Facial Skin Rejuvenation [Response to Letter]
Microneedling and fractional CO2 laser are compared as methods for delivering stem cell secretomes for skin rejuvenation.
research Three‐in‐One Multifunctional Metal–Organic Gel‐Encapsulated Microneedles for Programmed Treatment of Infected Wounds
The microneedles effectively treat infected wounds by killing bacteria, reducing inflammation, and promoting healing.
research Injection/Application of Micrografts
Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
research Creating slits to the right depth: Innovative use of micropore tape for depth control on an 18-gauge needle in hair restoration surgery
The document concludes that using micropore tape on an 18-gauge needle can control depth in hair restoration surgery, reducing scalp trauma and complications.
research Recyclable PolymerizableDeep Eutectic Solvent-BasedThree-Dimensional-Printed Dissolving Microneedles with pH-ResponsiveDelivery of ZIF-8-Loaded Minoxidil for Hair Loss Therapy
The new microneedle system effectively delivers minoxidil for hair regrowth with minimal side effects.
research TREATMENT OF ALOPECIA AREATA WITH ORAL METHYLPREDNISOLONE COMBINED WITH FRACTIONAL MICRONEEDLE RADIOFREQUENCY
Combining oral methylprednisolone with microneedle radiofrequency improves hair growth in alopecia areata but may cause pain and side effects.
research 원저 : 두피 및 눈썹 부위의 반흔에서 시행한 미세색소침착술 결과
Micropigmentation is a safe procedure that effectively improves the appearance of scars on the scalp and eyebrows, with most patients showing excellent or good results.