9 citations
,
March 2001 in “Clinics in dermatology” Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
5 citations
,
June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
2 citations
,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
research Acne
231 citations
,
April 2005 in “The New England Journal of Medicine” Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.
177 citations
,
July 2004 in “The Journal of Sexual Medicine” Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.
97 citations
,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
76 citations
,
December 2009 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
61 citations
,
January 2017 in “Human Reproduction Open” The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
59 citations
,
February 2021 in “BMJ” High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
51 citations
,
August 2012 in “Differentiation” Mouse genital development depends on male or female hormones for specific features.
47 citations
,
January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
45 citations
,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
43 citations
,
April 2011 in “AJP Endocrinology and Metabolism” Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
43 citations
,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
42 citations
,
January 2024 in “Frontiers in Endocrinology” Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
26 citations
,
October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
24 citations
,
April 2014 in “Oncotarget” Minoxidil can reduce functions related to androgen receptors.
23 citations
,
July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
21 citations
,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
21 citations
,
July 2014 in “Clinics in Dermatology” Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
17 citations
,
March 2016 in “Liver international” Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
16 citations
,
January 2023 in “Cureus” PCOS in teens causes hormonal imbalances, irregular periods, and can lead to infertility and other health issues.
11 citations
,
January 2011 in “Indian Dermatology Online Journal” Eating dairy and high glycemic foods may increase the risk of acne.
10 citations
,
May 2017 in “Symmetry” Higher androgen levels are linked to less asymmetry in !Kung San males.
8 citations
,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
7 citations
,
October 2012 in “S. Karger AG eBooks” Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.
5 citations
,
June 2022 in “Frontiers in Endocrinology” Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.
5 citations
,
June 2010 in “Endocrinología y Nutrición” Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.