February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
41 citations
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March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
10 citations
,
June 2006 in “Fertility and Sterility” The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.
26 citations
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March 2018 in “Experimental Dermatology” Prolactin may influence skin glands and could be a target for treating acne and skin aging.
12 citations
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April 2020 in “Medical hypotheses” Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.
11 citations
,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
November 2025 in “Cancers” Men with male pattern baldness may have a slightly higher risk of prostate cancer.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
22 citations
,
January 1995 in “The American Journal of Medicine” Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.
April 2024 in “Nigerian Postgraduate Medical Journal” Androgenetic alopecia is a common hair loss condition influenced by various factors and linked to psychosocial and cardiovascular issues.
August 1996 in “Journal of Pediatric and Adolescent Gynecology” The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.
December 2025 in “BENTHAM SCIENCE PUBLISHERS eBooks” PCOS often causes skin issues like excess hair, acne, hair thinning, and dark patches due to hormone imbalances and insulin resistance.
October 2025 in “Minerva Obstetrics and Gynecology” Choosing the right estroprogestin is crucial for effectively managing PCOS symptoms.
21 citations
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May 1988 in “Journal of The American Academy of Dermatology” The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.
29 citations
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February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
26 citations
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January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
40 citations
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October 2020 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” Higher androgen levels might make COVID-19 worse, especially in men.
3 citations
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October 2022 in “Hormone and Metabolic Research” Male hormones may increase the severity and death rates of COVID-19.
53 citations
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May 1986 in “Clinics in endocrinology and metabolism” Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
35 citations
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May 1986 in “Clinics in endocrinology and metabolism” The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
192 citations
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January 1976 in “The Journal of Clinical Endocrinology & Metabolism” Androgen levels increase with puberty and are linked to sexual hair development.
177 citations
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June 1991 in “The Journal of Clinical Endocrinology & Metabolism” Caucasian men have more chest hair and higher levels of certain androgen products than Chinese men.
174 citations
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July 2003 in “The Journal of Clinical Endocrinology & Metabolism” Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.
78 citations
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August 1996 in “The Journal of Clinical Endocrinology & Metabolism” The same gene mutation can cause different symptoms in family members.
78 citations
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March 1989 in “The Journal of Clinical Endocrinology & Metabolism” High-dose androgen therapy can help manage certain types of androgen resistance.
71 citations
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July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
67 citations
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April 1988 in “The Journal of Clinical Endocrinology & Metabolism” A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.
43 citations
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April 2011 in “AJP Endocrinology and Metabolism” Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
24 citations
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March 2003 in “Best Practice & Research Clinical Endocrinology & Metabolism” Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
19 citations
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March 2004 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone and letrozole treatment speeds up puberty in boys with delayed development.