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5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.

3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

Women with PCOS have distinct retinal changes compared to healthy women.

Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Vitamin D can help reduce depression in people with hypothyroidism.

Finasteride may increase the risk of suicidality and depression, especially in younger people.

Vitamin D helps reduce depression in people with autoimmune thyroiditis and hypothyroidism.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Allopregnanolone changes gene expression in glioblastoma cells.

Dutasteride helps reduce heavy drinking, especially for those who drink to cope.

Finasteride use may increase suicidality risk, especially in young men.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Blood hormone levels don't accurately show brain hormone levels in males.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Hair analysis shows low progesterone in anorexia patients, unchanged by short-term weight gain.

Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Mitotane changes steroid breakdown, affecting cortisol availability.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Women with PCOS may have a higher risk of Alzheimer's disease.

SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.

Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.

Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.