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Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase enzyme affects hormone levels, influencing conditions like acne and hair loss.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Androgenic alopecia can be treated with minoxidil, finasteride, and hormonal therapy.

DHT deficiency in rats reduces sperm content and affects testis structure over time.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The method accurately measures seven androgens in plasma and shows different hormone levels in females with acne and obesity.

Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.

Androgens improve memory in adolescent male rats by acting on brain receptors.

Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.

Both treatments reduced androgen levels and hair growth in women with hirsutism.

The treatment effectively reduces menopausal symptoms and is well tolerated.

Androgenic alopecia is male or female pattern baldness.

Finasteride may improve prostate cancer treatment outcomes.

Using single dermal papillae is unreliable for analyzing androgen metabolism in hair follicles.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Activating androgen receptors in muscle can increase muscle mass and reduce fat.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

GI197111X is best dissolved in Capmul MCM for trials.

Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.