February 2026 in “International Journal of Clinical Dermatology” Certain probiotics can help improve skin conditions like atopic dermatitis, but more research is needed.
Polygonum multiflorum may help treat hair loss but can be toxic to the liver.
March 2025 in “Journal of Clinical Medicine” Iron chelators can effectively reduce hair loss and improve hair growth in autoimmune alopecia.
February 2024 in “International journal of molecular sciences” Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
August 2023 in “Medical Hypotheses” Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
488 citations
,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
53 citations
,
July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
47 citations
,
April 2021 in “BMC Medical Genomics” Certain gene variants can influence acne risk and severity.
22 citations
,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
5 citations
,
November 1992 in “Current problems in dermatology” Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
4 citations
,
January 2025 in “The Journal of Cell Biology” Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.
November 2023 in “Frontiers in Medicine” The method effectively mimics shaving damage on skin for testing skincare products.
245 citations
,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
December 2025 in “International Journal of Innovative Technologies in Social Science” Alcohol and nicotine harm skin health and speed up aging.
45 citations
,
March 2020 in “International Journal of Nanomedicine” Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.
August 2025 in “International Journal of Molecular Sciences” Osmanthus fragrans var. aurantiacus Makino may help treat inflammation due to its antioxidative and anti-inflammatory properties.
22 citations
,
August 2009 in “Evidence-based Complementary and Alternative Medicine” The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.
4 citations
,
March 2023 in “Journal of medical case reports” Taking too much vitamin E caused a young man's blood clotting problems, which improved after he stopped the vitamin E and got treatment.
17 citations
,
July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.
53 citations
,
July 2018 in “Drug design, development and therapy” Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
9 citations
,
April 2024 in “Metabolites” Cannabis has anti-inflammatory and antimicrobial properties, but more research is needed on its effects on plant and aquatic animal pathogens.
20 citations
,
December 2013 in “Journal of Dermatology” UV-B light increases inflammation-related substances in acne-related skin cells.
13 citations
,
April 2022 in “Journal of Mind and Medical Sciences” IBD treatment is complex and requires personalized approaches due to varying patient responses.
April 2026 in “Frontiers in Cell and Developmental Biology” GPCRs are vital for wound healing by affecting cell growth and immune response.
1 citations
,
February 2025 in “Journal of the Neurological Sciences” Beta-trace protein may help diagnose and predict treatment response in certain nerve disorders.
68 citations
,
September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
271 citations
,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
4 citations
,
December 2020 in “Scientific Reports” The plant extract mixture improves skin health by reducing inflammation, boosting collagen, and supporting anti-aging.
1 citations
,
April 2015 in “Cytokine” Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
1 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” Platelet-Rich Plasma treatment improved hair growth and reduced inflammation in patients with patchy hair loss, but not in total hair loss, and Optical Coherence Tomography was useful in tracking this progress.