19 citations
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January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
2 citations
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June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
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July 2021 in “Frontiers in Oncology” Neoadjuvant endocrine therapy led to a better future outlook than chemotherapy, with no major quality of life differences.
3 citations
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August 2025 in “Stem Cell Research & Therapy” Adipose-derived stem cells show promise in treating hair loss by promoting hair regrowth and improving hair follicle function.
2 citations
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September 1989 in “PubMed” Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.
502 citations
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February 2008 in “The Journal of Clinical Endocrinology & Metabolism” Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
110 citations
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September 2017 in “Molecules” Forsythiae Fructus has anti-inflammatory, antibacterial, and antiviral properties, with differences between unripe and ripe forms important for clinical use.
89 citations
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August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
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November 2025 in “Molecules” Ellagic acid can help treat skin issues, but its effectiveness is limited by poor absorption, so new delivery methods are being explored.
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June 2023 in “Cureus” Spironolactone may help improve symptoms and tear quality in dry eye disease.
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January 2022 in “Journal of Biosciences and Medicines” Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
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July 2017 in “Clinical research in dermatology” Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
4 citations
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October 2020 in “Actas Dermo-Sifiliográficas” Common dermatology drugs were considered but are controversial for COVID-19 treatment.
July 2025 in “American Journal of Clinical Dermatology” Alopecia treatments like 5α-reductase inhibitors and spironolactone are safe for breast cancer patients and high-risk women.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” Vitex negundo has potential health benefits, including anti-inflammatory and anti-cancer effects.
29 citations
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July 2012 in “Fertility and Sterility” Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
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April 1997 in “Human reproduction” Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.
21 citations
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June 2022 in “Molecules” Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
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January 1996 in “Gynecological Endocrinology” Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
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May 2020 in “Biomolecules” Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
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September 2012 in “Critical Reviews in Food Science and Nutrition” Wheat straw is valuable for its health benefits and various industrial uses.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
34 citations
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July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
29 citations
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January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
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January 2017 in “Journal of Clinical Trials & Patenting” The lotion safely and effectively reduces unwanted hair growth.
45 citations
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January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
August 2024 in “Aesthetic Plastic Surgery” Exosome treatment safely increases hair density in male patients with androgenetic alopecia.
55 citations
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May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.