19 citations
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June 2002 in “American Journal of Dermatopathology” Apoptosis contributes to hair loss in androgenetic alopecia.
November 2025 in “Biomedicines” Targeting pyroptosis may offer new treatments for alopecia areata, but more research is needed.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
48 citations
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April 2023 in “Aging Cell” Targeting cellular senescence may improve skin aging and disorders.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
August 2013 in “Nature Reviews Drug Discovery” New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
November 2025 in “Eurasian journal of applied biotechnology” Combining L-cysteine, NAC, and a MET inhibitor significantly kills cervical cancer cells.
1 citations
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March 2003 in “Journal of Investigative Dermatology” Early sunburn treatment with certain inhibitors may reduce skin cancer risk.
April 2023 in “Journal of Investigative Dermatology” ALRN-6924 can protect hair follicles from chemotherapy damage by temporarily stopping cell division.
19 citations
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August 2008 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
7 citations
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August 2020 in “Current topics in medicinal chemistry” New cancer treatments aim to reduce side effects and improve effectiveness.
54 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”
May 2023 in “Research Square (Research Square)” Botulinum toxin type A helps treat hair loss by stopping cell death in hair follicles through a process involving certain non-coding RNAs and a protein called Bax.
14 citations
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January 2006 in “Skin pharmacology and physiology” Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
3 citations
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April 2022 in “Research Square (Research Square)” PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
5 citations
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June 2022 in “Biophysical Journal” TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
Regulating cell death is crucial for skin health and treating inflammatory skin diseases.
7 citations
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August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
2 citations
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November 2024 in “In Silico Pharmacology” 2 citations
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January 2016 in “Sarcoma” Inducing survivin in normal tissues can protect against radiation damage.
January 2000 in “Cambio 16” Bcl-2 affects hair growth and pigmentation by controlling cell death.
3 citations
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October 2025 in “Cancer” PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
8 citations
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February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
18 citations
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February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
6 citations
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May 2024 in “Frontiers in Pharmacology” Natural products may help treat Non-Small Cell Lung Cancer by causing cancer cell death through ferroptosis.
VDAC2 promotes cell death in cashmere goat hair follicles through the P53 pathway.
76 citations
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July 2009 in “Neuroscience” Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.
4 citations
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July 2025 in “Frontiers in Pharmacology” Cooling with antioxidants helps protect hair during chemotherapy.
78 citations
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June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.