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SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.

Doctors should consider SLE in males even if antinuclear antibody tests are negative.

Patients with thyroid disorders show different symptoms and antibody levels.

Alopecia areata patients often have undetected thyroid issues, so routine thyroid screening is recommended.

Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.

Early screening and HPV vaccination reduce cervical cancer risk.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Anifrolumab may help improve symptoms in patients with overlapping autoimmune diseases.

Androgen lowering medications don't significantly change HCV-related liver cancer risk in men.

Thyroid disorders can cause skin issues in children, so early detection and screening are important.

A young woman with lupus developed tuberculosis due to weakened immunity from her medication, showing the need for better TB screening in such patients.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

A woman with a rare type of dermatomyositis improved with low-dose prednisone and methotrexate.

A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.

Doctors should watch for and treat hormonal issues in obese patients beyond just diabetes.

Two patients developed complete hair loss after Alemtuzumab treatment for MS, with no regrowth after two years.

Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.

Hair testing is a reliable method for detecting workplace drug use when done with proper sample preparation and confirmation.

A potential link exists between unexplained hormone deficiency, hair loss, and testicular tumors, suggesting thorough screening is needed.

Early diagnosis and treatment are crucial for CAPS, and Eculizumab can be effective.