research 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivo
17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
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390-420 / 1000+ resultsresearch Androgen Therapy for Postmenopausal Women; What is New?
research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol
Testosterone affects vascular cells directly without converting to estradiol.
research A systematic review of antiandrogens and feminization in transgender women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Human skin
Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
research Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling
Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman
Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
research The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women
Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
research Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
research Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells
17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.
research Beneficios y riesgos de los implantes de testosterona en mujeres: revisión sistemática de la literatura
The risks of testosterone implants in women outweigh the benefits.
research Persistent Gynecomastia due to Short-term Low-dose Finasteride for Androgenetic Alopecia
A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
research Progestogens in menopausal hormone therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Androgen Treatment in Women
Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.
research Current concepts in aesthetic endocrinology
Estrogens can slow skin aging after menopause, but can't restore youthful skin.
research Impacts of Anabolic-androgenic steroid supplementation on female health and offspring: Mechanisms, side effects, and medical perspectives
Anabolic-androgenic steroids can harm women's health and their offspring.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Using 5 alpha reductase inhibitors safely: What primary care physicians need to know
5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
research REAL WORLD STUDY ON ORAL ESTRADIOL TREATMENT IN TRANSGENDER WOMEN
GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
research Menopause and aging, quality of life and sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
research Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen
Estrogen can temporarily slow down hair growth but this can be reversed.
research Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α
17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.
research Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know?
5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.
research The use of testosterone after menopause
Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Research progress on drug-induced gynecomastia
Stopping the drug usually helps, but tamoxifen or surgery may be needed if symptoms persist.
research Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome
The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
research Effects of antiandrogen therapy of cyproteron acetate on androgen effects on the skin including androgenetic alopecia in menopausal women – case report: 10 years follow up –
Cyproterone acetate therapy improved hair loss and reduced testosterone levels in a menopausal woman.