25 citations
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April 1988 in “Geburtshilfe und Frauenheilkunde” Treatment balancing hormones stopped hair loss in most women with androgenetic alopecia.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
January 2025 in “American Journal of Translational Research” The combination therapy effectively treats infertility in PCOS without major side effects.
24 citations
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
January 2026 in “Endocrinology” 87 citations
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April 1973 in “Endocrinology” The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
20 citations
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January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
282 citations
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October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
2 citations
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September 1971 in “Metabolism, clinical and experimental” Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.
28 citations
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May 1986 in “Clinics in endocrinology and metabolism” New compounds may soon be tested to treat excessive hair growth in women.
306 citations
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August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
58 citations
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February 2018 in “Journal of cosmetic dermatology” Estrogen helps keep skin healthy and may make women look younger and more attractive.
May 2024 in “Reactions weekly” 25 citations
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August 1989 in “Seminars in reproductive medicine” Birth control pills are effective for treating women with too much male hormone.
October 2024 in “Journal of the Endocrine Society” A rare ovarian tumor caused high testosterone in a postmenopausal woman, resolved by surgery.
65 citations
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April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
October 2024 in “Journal of the Endocrine Society” Gender-affirming hormone therapy affects metabolism differently based on treatment type.
14 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” 31 citations
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January 2008 in “Gynecological endocrinology” Both birth control pills improved hormone levels and skin conditions in women with hyperandrogenism, but the one with drospirenone was more effective.
February 2025 in “Prospects in Pharmaceutical Sciences” Clascoterone is a promising topical treatment for hair loss and acne with fewer side effects.
November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” Thorough evaluation is crucial for postmenopausal women with virilization to detect rare ovarian tumors.
January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
7 citations
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August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
7 citations
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August 2006 in “Maturitas” Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
August 2012 in “Open Repository and Bibliography (University of Liège)” A castrated dog developed hair loss and prostate issues from long-term exposure to estrogen cream.
4 citations
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April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
6 citations
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September 2024 in “Journal of the American Academy of Dermatology” Oral 5-alpha reductase inhibitors do not increase breast cancer or benign breast disorder risk in women.