research Recent Advances in Wound Healing, Tissue Repair, Regeneration and Scar Management
New therapies and personalized approaches improve wound healing and patient quality of life.
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research Polydeoxyribonucleotide in Skincare and Cosmetics: Mechanisms, Therapeutic Applications, and Advancements Beyond Wound Healing and Anti-aging
PDRN from trout sperm helps skin and hair regeneration but is costly and complex to produce.
research Immunomodulatory Potential and Biocompatibility of Chitosan–Hydroxyapatite Biocomposites for Tissue Engineering
Chitosan–hydroxyapatite biocomposites are promising for tissue engineering due to their safety and ability to support healing.
research Potential of the Nano-Encapsulation of Antioxidant Molecules in Wound Healing Applications: An Innovative Strategy to Enhance the Bio-Profile
Combining polymers and lipids may improve antioxidant delivery for wound healing, but practical challenges remain.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Success and Controversy of Natural Products as Therapeutic Modulators of Wnt Signaling and Its Interplay with Oxidative Stress: Comprehensive Review Across Compound Classes and Experimental Systems
Natural products show promise for treating diseases but need more research to understand and use them effectively.
research Polymeric Nanohydrogel in Topical Drug Delivery System
Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
research A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds
Spironolactone nano-formulations show promise for treating skin disorders, but more research is needed for safety and effectiveness.
research Characterization of the in vitro, ex vivo, and in vivo Efficacy of the Antimicrobial Peptide DPK-060 Used for Topical Treatment
DPK-060 in poloxamer gel effectively treats skin infections, but nanocarriers don't enhance its efficacy.
research Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides
Cubosomes enhance antimicrobial peptide stability and effectiveness.
research 558 The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research Role of Human Skin Antimicrobial Peptides in Psoriasis
Inflammation in psoriasis may trigger antimicrobial peptides and cell death.
research 1318 Both lesional and non-lesional skin from acne patients shows robust IL-17-skewing and upregulation of antimicrobial peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Infectious Diseases 2015: The antimicrobial peptides delivery strategies based on nanotechnology to treat infectious diseases - Groo Anne-Claire - University of Angers
Nanotechnology can effectively deliver antimicrobial peptides for treating infections.
research 495 OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy?
A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research 129 Targeted inhibition of EGFR reduces anti-microbial defense mechanisms at the hair canal
Inhibiting EGFR weakens skin's defense against bacteria.
research The Epidermal Vitamin D System and Innate Immunity: Some More Light Shed on This Unique Photoendocrine System?
Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.
research Exosome laden sprayable thermo-sensitive polysaccharide-based hydrogel for enhanced burn wound healing
The hydrogel improves burn healing by promoting tissue growth and reducing inflammation.
research Keratin biomaterials for wound healing and tissue regeneration: A promising approach in biomedical applications
Keratin biomaterials could help heal wounds and regenerate tissue, but more testing is needed.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research 有效成分으로 접근해본 두피노화방지(Scalp Anti-Ageing)와 탈모방지(Anti-Hair loss)
GHK-Cu and propolis may help prevent scalp aging and hair loss.
research 498 Innate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT
DHT may reduce inflammation caused by certain bacteria in skin cells.
research 856 Topical application of newly developed pseudoceramide improved both skin and hair barrier functions
Applying pseudoceramide improved skin and hair health.
research Ganoderma: The wild mushroom with wonderful health benefits
The Ganoderma mushroom has many health benefits, including anti-cancer properties.
research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology
The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
research Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont
Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
research Clinical Snippets
Ferulic acid helps stabilize vitamins C and E for better skin protection from the sun, certain compounds may promote hair growth, atopic dermatitis patients have lower skin defense molecules, older men are more likely to get a type of skin cancer, and a substance called relaxin may prevent age-related skin thickening.
research Ethnobotany, Pharmacology and Major Bioactive Metabolites from Impatiens Genus Plants and their Related Applications
Impatiens plants have potential health benefits but need more research.
research The human tri-peptide GHK and tissue remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.