188 citations
,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
98 citations
,
May 2020 in “Journal of Functional Morphology and Kinesiology” Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
2 citations
,
May 2024 in “Journal of science and medicine in sport” Exercise is crucial for managing polycystic ovary syndrome (PCOS) and improving overall health.
63 citations
,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
Androgen receptors significantly affect hair loss in women with androgenetic alopecia.
May 2008 in “Hair transplant forum international” A genetic test can identify people at risk of male pattern baldness early, allowing for quicker treatment.
1 citations
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August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
1 citations
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May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
August 2023 in “Drug Design Development and Therapy” Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
23 citations
,
December 2013 in “Molecular cancer therapeutics” Breast cancer treatments work better with AR activation, improving results and reducing side effects.
19 citations
,
July 2005 in “Steroids” Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
3 citations
,
June 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.
11 citations
,
May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
17 citations
,
September 2024 in “Molecules” Turmeric essential oil compounds have potential as safe, effective drugs.
24 citations
,
March 2024 in “Antioxidants” Ginger and cinnamon can help manage PCOS and related disorders by reducing oxidative stress and inflammation.
3 citations
,
May 2021 in “Molecules” Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.
March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences” A new method accurately measures nine steroid hormones in human serum with high sensitivity.
16 citations
,
March 2011 in “Dermatologic Therapy” Women with greater androgen sensitivity respond better to finasteride for hair loss.
October 2025 in “Scientific Reports” AR gene variations don't affect aging markers in men.
4 citations
,
January 2023 in “Pharmacology” Atorvastatin is less effective for women with Hashimoto's thyroiditis.
53 citations
,
January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
6 citations
,
January 2013 in “Genetics and Molecular Research” Women with hair loss have more androgen receptors in certain hair follicles.
June 2023 in “Journal of Cosmetic Dermatology” AI and AR are improving cosmetic dermatology but face challenges like data quality and ethical concerns.
May 2023 in “Experimental Dermatology” Male pattern hair loss may be linked to the developmental origins of hair follicles.
The conclusion is that a treatment called cp-asiAR can reduce hair loss and promote hair growth, making it a potential new therapy for androgenetic alopecia.
37 citations
,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
1 citations
,
January 2006 Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
3 citations
,
February 2021 in “Molecules” A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
May 2023 in “Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy” A new green method accurately measures finasteride and tadalafil in drugs and plasma.