74 citations
,
November 1975 in “Archives of dermatology” Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.
August 2015 in “MOJ proteomics & bioinformatics” ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
12 citations
,
May 2016 in “British Journal of Dermatology” AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
6 citations
,
January 2022 in “Journal of Investigative Dermatology” Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
July 2024 in “Journal of Investigative Dermatology” The Fas/FasL pathway may play a role in alopecia areata.
2 citations
,
February 2014 in “Hair therapy & transplantation” Alopecia Areata is an autoimmune condition causing hair loss, influenced by genetics, environment, and possibly improved by anti-MIF therapy, with many patients experiencing regrowth within a year.
13 citations
,
August 2021 in “Frontiers in Bioengineering and Biotechnology” Exosomes from fat stem cells can reduce fat cell formation.
46 citations
,
September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
9 citations
,
December 1996 in “Cell Biology and Toxicology” Hair follicle cells produce VEGF, which can promote blood vessel cell growth and movement.
12 citations
,
May 2016 in “Experimental Dermatology” A new skin model from hair follicles is a safer, simpler alternative for skin tests.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” Age-related hair loss is linked to changes in blood vessels, stem cells, and aging cells, and understanding these can help keep hair healthy as we age.
15 citations
,
May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
August 2018 in “The Molecular Biology Society of Japan” 3 citations
,
November 2020 in “PubMed” Stiffer hydrogels better promote stem cells turning into hair follicle cells.
14 citations
,
May 2019 in “Experimental Dermatology” Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
61 citations
,
February 2003 in “Experimental Dermatology” Soy oil and genistein reduce hair loss risk in mice.
13 citations
,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
April 2015 in “Plastic and Reconstructive Surgery” TLR3 activation helps improve skin and hair follicle healing in mice.
43 citations
,
April 2021 in “Angiogenesis” Lymphatic vessels develop from various cell types and mechanisms, not just veins.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
19 citations
,
January 2018 in “Scientific Reports” Non-immune factors play a significant role in alopecia areata.
81 citations
,
May 1986 in “Journal of Investigative Dermatology”
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
85 citations
,
October 2006 in “Current opinion in cell biology” Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
23 citations
,
May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
7 citations
,
October 2020 in “Wiener medizinische Wochenschrift” THA is a rare condition with no significant clinical consequences if thyroid function is normal.